Skip Navigation


American Journal of Epidemiology Advance Access originally published online on April 26, 2006
American Journal of Epidemiology 2006 163(10):938-949; doi:10.1093/aje/kwj114
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
163/10/938    most recent
kwj114v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (14)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Corrada, M. M.
Right arrow Articles by Paganini-Hill, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Corrada, M. M.
Right arrow Articles by Paganini-Hill, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology Copyright © 2006 by the Johns Hopkins Bloomberg School of Public Health All rights reserved; printed in U.S.A.

Original Contribution

Association of Body Mass Index and Weight Change with All-Cause Mortality in the Elderly

María M. Corrada1,2, Claudia H. Kawas1,2,3, Farah Mozaffar2 and Annlia Paganini-Hill4

1 Department of Neurology, School of Medicine, University of California, Irvine, CA
2 Institute for Brain Aging and Dementia, University of California, Irvine, CA
3 Department of Neurobiology and Behavior, School of Biological Sciences, University of California, Irvine, CA
4 Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA

Correspondence to Dr. María M. Corrada, Hewitt Hall, Room 1513, Department of Neurology, School of Medicine, University of California, Irvine, CA 92697-1400 (e-mail: mcorrada{at}uci.edu).

The authors explored the relation of body mass index (BMI; weight (kg)/height (m)2) and weight change to all-cause mortality in the elderly, using data from a large, population-based California cohort study, the Leisure World Cohort Study. They estimated relative risks of mortality associated with self-reported BMI at study entry, BMI at age 21 years, and weight change between age 21 and study entry. Participants were categorized as underweight (BMI <18.5), normal weight (BMI 18.5–24.9), overweight (BMI 25–29.9), or obese (BMI ≥30). Of 13,451 participants aged 73 years (on average) at study entry (1981–1985), 11,203 died during 23 years of follow-up (1981–2004). Relative to normal weight, being underweight (relative risk (RR) = 1.51, 95% confidence interval (CI): 1.38, 1.65) or obese (RR = 1.25, 95% CI: 1.13, 1.38) at study entry was associated with increased mortality. People who were either overweight or obese at age 21 also had increased mortality (RR = 1.17, 95% CI: 1.09, 1.25). Participants who lost weight between age 21 and study entry had increased mortality regardless of their BMI category at age 21. Obesity was significantly associated with increased mortality only among persons under age 75 years and among never or past smokers. This study highlights the influence on older-age mortality risk of being overweight or obese in young adulthood and underweight or obese in later life.

aged; body mass index; body weight changes; longevity; mortality; risk factors

Abbreviations: BMI, body mass index; CI, confidence interval; RR, relative risk


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Age AgeingHome page
V. Hirani and J. Mindell
A comparison of measured height and demi-span equivalent height in the assessment of body mass index among people aged 65 years and over in England
Age Ageing, May 1, 2008; 37(3): 311 - 317.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
P. M. Nilsson
Is Weight Loss Beneficial for Reduction of Morbidity and Mortality?: What is the controversy about?
Diabetes Care, February 1, 2008; 31(Supplement_2): S278 - S283.
[Abstract] [Full Text] [PDF]

Home page
 J. Gerontol. A Biol. Sci. Med. Sci.Home page
D. R. Bouchard, S. Beliaeff, I. J. Dionne, and M. Brochu
Fat Mass But Not Fat-Free Mass Is Related to Physical Capacity in Well-Functioning Older Individuals: Nutrition as a Determinant of Successful Aging (NuAge) The Quebec Longitudinal Study
J. Gerontol. A Biol. Sci. Med. Sci., December 1, 2007; 62(12): 1382 - 1388.
[Abstract] [Full Text] [PDF]

Home page
 J. Gerontol. A Biol. Sci. Med. Sci.Home page
J. L. Locher, D. L. Roth, C. S. Ritchie, K. Cox, P. Sawyer, E. V. Bodner, and R. M. Allman
Body Mass Index, Weight Loss, and Mortality in Community-Dwelling Older Adults
J. Gerontol. A Biol. Sci. Med. Sci., December 1, 2007; 62(12): 1389 - 1392.
[Abstract] [Full Text] [PDF]

Home page
 Am J EpidemiolHome page
G. Logroscino, H. D. Sesso, R. S. Paffenbarger Jr, and I-M. Lee
Body Mass Index and Risk of Parkinson's Disease: A Prospective Cohort Study
Am. J. Epidemiol., November 15, 2007; 166(10): 1186 - 1190.
[Abstract] [Full Text] [PDF]

Home page
 AJGPHome page
N. Sachs-Ericsson, A. B. Burns, K. H. Gordon, L. A. Eckel, S. A. Wonderlich, R. D. Crosby, and D. G. Blazer
Body Mass Index and Depressive Symptoms in Older Adults: The Moderating Roles of Race, Sex, and Socioeconomic Status
Am J Geriatr Psychiatry, September 1, 2007; 15(9): 815 - 825.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
D. Drogan, K. Hoffmann, M. Schulz, M. M. Bergmann, H. Boeing, and C. Weikert
A Food Pattern Predicting Prospective Weight Change Is Associated with Risk of Fatal but Not with Nonfatal Cardiovascular Disease
J. Nutr., August 1, 2007; 137(8): 1961 - 1967.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. L. T. Uusitalo, E. Vanninen, E. Levalahti, M. C. Battie, T. Videman, and J. Kaprio
Role of genetic and environmental influences on heart rate variability in middle-aged men
Am J Physiol Heart Circ Physiol, August 1, 2007; 293(2): H1013 - H1022.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Public HealthHome page
C. M. Dolan, H. Kraemer, W. Browner, K. Ensrud, and J. L. Kelsey
Associations Between Body Composition, Anthropometry, and Mortality in Women Aged 65 Years and Older
Am J Public Health, May 1, 2007; 97(5): 913 - 918.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.