ORIGINAL CONTRIBUTIONS |
Seasonal Analyses of Air Pollution and Mortality in 100 US Cities
1 Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
2 Epidemiology and Biostatistics Section, National Center for Epidemiology, Carlos III Institute of Health, Madrid, Spain
3 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Correspondence to Dr. Roger D. Peng, Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205 (e-mail: rpeng{at}jhsph.edu).
Time series models relating short-term changes in air pollution levels to daily mortality counts typically assume that the effects of air pollution on the log relative rate of mortality do not vary with time. However, these short-term effects might plausibly vary by season. Changes in the sources of air pollution and meteorology can result in changes in characteristics of the air pollution mixture across seasons. The authors developed Bayesian semiparametric hierarchical models for estimating time-varying effects of pollution on mortality in multisite time series studies. The methods were applied to the database of the National Morbidity and Mortality Air Pollution Study, which includes data for 100 US cities, for the period 1987–2000. At the national level, a 10-µg/m3 increase in particulate matter less than 10 µm in aerodynamic diameter at a 1-day lag was associated with 0.15% (95% posterior interval (PI): –0.08, 0.39), 0.14% (95% PI: –0.14, 0.42), 0.36% (95% PI: 0.11, 0.61), and 0.14% (95% PI: –0.06, 0.34) increases in mortality for winter, spring, summer, and fall, respectively. An analysis by geographic region found a strong seasonal pattern in the Northeast (with a peak in summer) and little seasonal variation in the southern regions of the country. These results provide useful information for understanding particle toxicity and guiding future analyses of particle constituent data.
air pollution; epidemiologic methods; models; statistical; mortality; seasons
Abbreviations: NMMAPS National Morbidity, Mortality, and Air Pollution Study; PI posterior interval; PM2.5 particulate matter less than 2.5 µm in aerodynamic diameter; PM10 particulate matter less than 10 µm in aerodynamic diameter
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