Copyright © 2004 by the Johns Hopkins Bloomberg School of Public Health
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Association between Alcoholic Beverage Consumption and Incidence of Coronary Heart Disease in Whites and Blacks
The Atherosclerosis Risk in Communities Study
1 Division of Cardiology, Clinical Hospital of Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
2 Department of Biostatistics, School of Public Health, University of North Carolina, Chapel Hill, NC.
3 Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN.
4 College of Public Health, University of Arkansas, Little Rock, AR.
5 Graduate Studies Program in Epidemiology, College of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
6 Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.
The authors evaluated the relation between consumption of alcoholic beverages and incidence of coronary heart disease in White and African-American participants in the Atherosclerosis Risk in Communities Study. The average duration of follow-up was 9.8 years between 1987 and 1998. The association was analyzed by means of Cox proportional hazards regression models. The authors found a positive association between ethanol consumption and incident coronary heart disease for Black men (for a 13-g/day increment in ethanol consumption, adjusted hazard ratio (HR) = 1.13, 95% confidence interval (CI): 1.01, 1.28) and an inverse association for White men (HR = 0.88, 95% CI: 0.79, 0.99). There was an inverse association of coronary heart disease with rare drinking (HR = 0.47, 95% CI: 0.28, 0.80) and with consumption of 
70 g of ethanol per week (HR = 0.49, 95% CI: 0.24, 0.98) in White women and with consumption of 210 g/week (HR = 0.56, 95% CI: 0.33, 0.95) in White men. In Black men, the association was positive for consumption of 140–<210 g/week (HR = 2.61, 95% CI: 1.11, 6.17). The contrasting findings in Whites and Black men in this cohort raise the question of whether the cardioprotective effect of alcohol is real or may be confounded by lifestyle characteristics of drinkers.
alcohol drinking; coronary disease
Abbreviations: Abbreviations: ARIC, Atherosclerosis Risk in Communities; CHD, coronary heart disease; HDL, high density lipoprotein.
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