Am J Epidemiol 2004; 159:702-706.
Copyright © 2004 by the Johns
Hopkins Bloomberg School of Public Health
ORIGINAL CONTRIBUTIONS |
A Modified Poisson Regression Approach to Prospective Studies with Binary Data
1 Robarts Clinical Trials, Robarts Research Institute, London, Ontario, Canada.
2 Department of Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada.
Relative risk is usually the parameter of interest in epidemiologic and medical studies. In this paper, the author proposes a modified Poisson regression approach (i.e., Poisson regression with a robust error variance) to estimate this effect measure directly. A simple 2-by-2 table is used to justify the validity of this approach. Results from a limited simulation study indicate that this approach is very reliable even with total sample sizes as small as 100. The method is illustrated with two data sets.
clinical trials; cohort studies; logistic regression; Mantel-Haenszel; odds ratio; relative risk
Abbreviations: Abbreviations: CI, confidence interval; RR, relative risk.
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 A. V Perruccio, J D. Power, and E. M Badley The relative impact of 13 chronic conditions across three different outcomes J Epidemiol Community Health, December 1, 2007; 61(12): 1056 - 1061. [Abstract] [Full Text] [PDF]
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Y. B. Cheung A Modified Least-Squares Regression Approach to the Estimation of Risk Difference Am. J. Epidemiol., December 1, 2007; 166(11): 1337 - 1344. [Abstract] [Full Text] [PDF]
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R. V. Walden, S. C. Taylor, N. I. Hansen, W. K. Poole, B. J. Stoll, D. Abuelo, B. R. Vohr, and for the National Institute of Child Health and Hum Major Congenital Anomalies Place Extremely Low Birth Weight Infants at Higher Risk for Poor Growth and Developmental Outcomes Pediatrics, December 1, 2007; 120(6): e1512 - e1519. [Abstract] [Full Text] [PDF]
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S. Mason, E. Knowles, B. Colwell, S. Dixon, J. Wardrope, R. Gorringe, H. Snooks, J. Perrin, and J. Nicholl Effectiveness of paramedic practitioners in attending 999 calls from elderly people in the community: cluster randomised controlled trial BMJ, November 3, 2007; 335(7626): 919 - 919. [Abstract] [Full Text] [PDF]
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 L. Fuccio, M. E. Minardi, R. M. Zagari, D. Grilli, N. Magrini, and F. Bazzoli Meta-analysis: Duration of First-Line Proton-Pump Inhibitor-Based Triple Therapy for Helicobacter pylori Eradication Ann Intern Med, October 16, 2007; 147(8): 553 - 562. [Abstract] [Full Text] [PDF]
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S. Taneja, S. Mandayam, Z. Z. Kayani, Y.-F. Kuo, and V. B. Shahinian Comparison of Stage at Diagnosis of Cancer in Patients Who Are on Dialysis versus the General Population Clin. J. Am. Soc. Nephrol., September 1, 2007; 2(5): 1008 - 1013. [Abstract] [Full Text] [PDF]
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E. L. Ding, N. R. Powe, J. E. Manson, N. S. Sherber, and J. B. Braunstein Sex Differences in Perceived Risks, Distrust, and Willingness to Participate in Clinical Trials: A Randomized Study of Cardiovascular Prevention Trials Arch Intern Med, May 14, 2007; 167(9): 905 - 912. [Abstract] [Full Text] [PDF]
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 T. I Ibiebele, J. C van der Pols, M. C. Hughes, G. C Marks, G. M Williams, and A. C Green Dietary pattern in association with squamous cell carcinoma of the skin: a prospective study Am. J. Clinical Nutrition, May 1, 2007; 85(5): 1401 - 1408. [Abstract] [Full Text] [PDF]
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