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Am J Epidemiol 2004; 159:167-174.
Copyright © 2004 by the Johns Hopkins Bloomberg School of Public Health


ORIGINAL CONTRIBUTIONS

Social Integration and Mortality: A Prospective Study of French Employees of Electricity of France–Gas of France

The GAZEL Cohort

Lisa F. Berkman1 , Maria Melchior2, Jean-François Chastang2, Isabelle Niedhammer2, Annette Leclerc2 and Marcel Goldberg2

1 Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA.
2 Institut National de la Santé et de la Recherche Médicale, Unité 88-IFR69, Saint-Maurice Cedex, France.

The authors investigated associations between social integration and all-cause and cause-specific mortality among French employees of Electricity of France–Gas of France. A total of 12,347 men aged 40–50 years in 1989 and 4,352 women aged 35–50 years in 1989 comprised the sample. In age-adjusted survival analyses for all causes of death, men who were least socially integrated were 4.42 times as likely to die during follow-up (1993–1999) as those with the highest level of integration (p < 0.0001). After adjustment for age, occupation, smoking, alcohol consumption, body mass index, self-reported health, depressive symptoms, and region of France, relative risks for men ranging from the least socially integrated to the most socially integrated were 2.70 (95% confidence interval (CI): 1.17, 6.23), 1.95 (95% CI: 1.25, 3.04), and 1.37 (95% CI: 0.92, 2.04) in comparison with the most integrated men. In multivariate cause-specific analyses, isolated men had elevated risks of dying from cancer (relative risk = 3.60) and from accidents and suicide (relative risk = 3.54). Among women, in multivariate analyses, the relative risk was 3.64 (95% CI: 0.72, 18.58). The small number of deaths among women (n = 29) limited statistical power and prohibited cause-specific analyses. These results suggest that in this employed cohort of middle-aged men and women, social integration is an important predictor of mortality.

interpersonal relations; mortality; social environment; social isolation; social support

Abbreviations: Abbreviations: CI, confidence interval; EDF-GDF, Electricity of France–Gas of France; RR, relative risk.


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