Am J Epidemiol 2003; 158:543-552.
Copyright © 2003 by Johns
Hopkins Bloomberg School of Public Health
ORIGINAL CONTRIBUTIONS |
Associations of Diabetes Mellitus and Ethnicity with Mortality in a Multiethnic Asian Population: Data from the 1992 Singapore National Health Survey
1 Epidemiology and Disease Control Division, Ministry of Health, Singapore, Republic of Singapore.
2 Department of Endocrinology, Singapore General Hospital, Singapore, Republic of Singapore.
Despite the high prevalence of diabetes mellitus, little is known about mortality associated with diabetes in Asia. Therefore, the authors followed 3,492 Chinese, Malay, and Asian Indian adults randomly selected from the general population in Singapore. Data on glucose tolerance, demographic characteristics, and other cardiovascular disease risk factors (lipid profile, blood pressure, smoking status, alcohol consumption, and obesity) were obtained in 1992. Vital status was determined as of December 31, 2001. There were 108 deaths over a period of 9 years. Impaired fasting glycemia or impaired glucose tolerance (IFG/IGT) (hazard ratio (HR) = 1.39, 95% confidence interval (CI): 0.84, 2.31) and diabetes mellitus (HR = 2.49, 95% CI: 1.58, 3.94) were associated with increased mortality after adjustment for age, gender, ethnic group, and educational level. Compared with Chinese with diabetes, Indians with diabetes experienced significantly greater mortality (HR = 3.86, 95% CI: 1.76, 8.44) after adjustment for gender, age, educational level, smoking, hypertension, alcohol intake, and obesity. Undiagnosed diabetes and IFG/IGT were more common than known diabetes and also were associated with increased mortality. For reduction of mortality associated with IFG/IGT and diabetes, the authors recommend a screening program to detect undiagnosed diabetes and IFG/IGT along with aggressive treatment of diabetes after diagnosis.
Asia; cardiovascular diseases; diabetes mellitus; ethnic groups; mortality
Abbreviations: Abbreviations: CI, confidence interval; HR, hazard ratio; IFG, impaired fasting glucose; IGT, impaired glucose tolerance.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  C. P. Wen, T. Y. D. Cheng, S. P. Tsai, H. L. Hsu, and S. L. Wang Increased Mortality Risks of Pre-Diabetes (Impaired Fasting Glucose) in Taiwan Diabetes Care, November 1, 2005; 28(11): 2756 - 2761. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. S. Tai, S. Y. Goh, J. J.M. Lee, M.-S. Wong, D. Heng, K. Hughes, S. K. Chew, J. Cutter, W. Chew, K. Gu, et al. Lowering the Criterion for Impaired Fasting Glucose: Impact on disease prevalence and associated risk of diabetes and ischemic heart disease Diabetes Care, July 1, 2004; 27(7): 1728 - 1734. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-E. Tan, S. Ma, D. Wai, S.-K. Chew, and E.-S. Tai Can We Apply the National Cholesterol Education Program Adult Treatment Panel Definition of the Metabolic Syndrome to Asians? Diabetes Care, May 1, 2004; 27(5): 1182 - 1186. [Abstract] [Full Text] [PDF]
|
|