Am J Epidemiol 2003; 158:1132-1138.
Copyright © 2003 by the Johns
Hopkins Bloomberg School of Public Health
ORIGINAL CONTRIBUTIONS |
Weight Loss: A Determinant of Hip Bone Loss in Older Men and Women
The Rancho Bernardo Study
From the Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, San Diego, CA.
The sex-specific effect of weight change on change in total hip bone mineral density was evaluated over 4 years (1992–1996) in 1,214 community-dwelling adults whose mean age at baseline was 71 years. Weight and bone mineral density (by dual-energy x-ray absorptiometry) were assessed at two study visits. The average bone loss was 0.5% per year in both sexes; 29% of men and 28% of women lost at least 1% of bone mineral density per year. More than one in five participants lost at least 1% of their body weight per year (21% of men and 23% of women). These weight losers were twice as likely as others to lose bone at the rate of at least 1% per year. In analyses controlling for age, baseline weight, and lifestyle, weight loss was the strongest independent predictor of bone loss (odds ratios were 1.53 for men and 1.56 for women). Persons with weight loss of at least 1% per year were more likely to report fair or poor health and functional limitation at the second visit and to die within 2 years of the second visit; however, most did not report declining health, and most survived for at least 2 additional years.
aged; bone density; osteoporosis; prospective studies; weight loss
Abbreviations: Abbreviation: BMD, bone mineral density.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  H. E. Meyer, A. J. Sogaard, J. A. Falch, L. Jorgensen, and N. Emaus Weight Change over Three Decades and the Risk of Osteoporosis in Men: The Norwegian Epidemiological Osteoporosis Studies (NOREPOS) Am. J. Epidemiol., August 15, 2008; 168(4): 454 - 460. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Barrett-Connor and C. A. Stuenkel Lifestyle Intervention and Postmenopausal Bone Density J. Clin. Endocrinol. Metab., October 1, 2007; 92(10): 3777 - 3779. [Full Text] [PDF]
|
|
|
|
|
|
H. A. Park, J. S. Lee, L. H. Kuller, and J. A. Cauley Effects of Weight Control during the Menopausal Transition on Bone Mineral Density J. Clin. Endocrinol. Metab., October 1, 2007; 92(10): 3809 - 3815. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. G. Wannamethee, A. G. Shaper, L. Lennon, and P. H. Whincup Height Loss in Older Men: Associations With Total Mortality and Incidence of Cardiovascular Disease Arch Intern Med, December 11, 2006; 166(22): 2546 - 2552. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 U. Ekelund, S. Brage, P. W Franks, S. Hennings, S. Emms, M.-Y. Wong, and N. J Wareham Physical activity energy expenditure predicts changes in body composition in middle-aged healthy whites: effect modification by age Am. J. Clinical Nutrition, May 1, 2005; 81(5): 964 - 969. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. E. Ensrud, R. L. Fullman, E. Barrett-Connor, J. A. Cauley, M. L. Stefanick, H. A. Fink, C. E. Lewis, E. Orwoll, and for the Osteoporotic Fractures in Men Study Resear Voluntary Weight Reduction in Older Men Increases Hip Bone Loss: The Osteoporotic Fractures in Men Study J. Clin. Endocrinol. Metab., April 1, 2005; 90(4): 1998 - 2004. [Abstract] [Full Text] [PDF]
|
|