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Am J Epidemiol 2003; 157:467-471.
Copyright © 2003 by Johns Hopkins Bloomberg School of Public Health


ORIGINAL CONTRIBUTIONS

Variability in the Incidence of Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Infection among Young Injecting Drug Users in New York City

Don C. Des Jarlais1,2,, Theresa Diaz3, Theresa Perlis2, David Vlahov3, Carey Maslow2, Mary Latka3, Russell Rockwell2, Vincent Edwards3, Samuel R. Friedman2, Edgar Monterroso4, Ian Williams4 and Richard S. Garfein4

1 Baron Edmond de Rothschild Chemical Dependency Institute, Beth Israel Medical Center, New York, NY.
2 National Development and Research Institutes, Center for AIDS Research, New York, NY.
3 New York Academy of Medicine, Center for Urban Epidemiologic Studies, New York, NY.
4 Thailand–United States Collaboration, Centers for Disease Control and Prevention, Atlanta, GA.

Cohort studies of young (aged 18–30 years) injecting drug users recruited in 1997–1999 in the Harlem and Lower East Side areas of New York City, New York, were used to assess the incidence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). The authors found that HIV incidence was low at both sites: 0.8/100 person-years at the Harlem site and 0/100 person-years at the Lower East Side site. In contrast, HBV incidence was moderate (12.2/100 person-years) at the Harlem site and high (30.7/100 person-years) at the Lower East Side site. Similarly, HCV incidence was moderate (9.3/100 person-years) at the Harlem site and high (34.0/100 person-years) at the Lower East Side site. Results show that high rates of HBV and HCV transmission do not imply high rates of HIV transmission, even within an area of high HIV seroprevalence.

cohort studies; hepatitis B virus; hepatitis C-like viruses; HIV; injections, intravenous; substance-related disorders

Abbreviations: Abbreviations: HBV, hepatitis B virus; HCV, hepatitis C virus; HIV, human immunodeficiency virus.


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