Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (18)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Nagata, C.
Right arrow Articles by Shimizu, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nagata, C.
Right arrow Articles by Shimizu, H.
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Am J Epidemiol 2002; 156:824-831.
Copyright © 2002 by Johns Hopkins Bloomberg School of Public Health


ORIGINAL CONTRIBUTIONS

Soy and Fish Oil Intake and Mortality in a Japanese Community

Chisato Nagata, Naoyoshi Takatsuka and Hiroyuki Shimizu

From the Department of Public Health, Gifu University School of Medicine, Gifu, Japan.

The relation between intake of fish and soy products and subsequent all-cause and cause-specific mortality was examined in a cohort of 13,355 male and 15,724 female residents of Takayama, Gifu, Japan. A diet that included soy and fish intake was assessed in 1992 by using a validated semiquantitative food frequency questionnaire. Over 7 years of follow-up, 2,062 participants (1,163 men and 899 women) died. For men, the highest compared with the lowest quintile of total soy product intake was marginally significantly inversely associated with total mortality after adjustment for total energy and nondietary covariates (hazard ratio = 0.83, 95% confidence interval: 0.69, 1.01; p for trend = 0.07). After adjustment for nondietary covariates, a decreased hazard ratio for the highest compared with the lowest quintile of total soy product intake was also observed for women (hazard ratio = 0.83, 95% confidence interval: 0.68, 1.02; p for trend = 0.04). Additional adjustment for dietary factors significantly associated with total mortality did not attenuate these associations. For women but not for men, n-3 fatty acids from fish were significantly inversely associated with total mortality. Results showed that soy intake may have moderate but beneficial effects on total mortality.

cohort studies; diet; fishes; mortality; soybeans

Abbreviations: Abbreviations: CI, confidence interval; ICD-10, International Classification of Diseases, Tenth Revision.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
J. Nutr.Home page
W. S. Harris, D. Mozaffarian, M. Lefevre, C. D. Toner, J. Colombo, S. C. Cunnane, J. M. Holden, D. M. Klurfeld, M. C. Morris, and J. Whelan
Towards Establishing Dietary Reference Intakes for Eicosapentaenoic and Docosahexaenoic Acids
J. Nutr., April 1, 2009; 139(4): 804S - 819S.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
A. Pan, O. H. Franco, J. Ye, W. Demark-Wahnefried, X. Ye, Z. Yu, H. Li, and X. Lin
Soy Protein Intake Has Sex-Specific Effects on the Risk of Metabolic Syndrome in Middle-Aged and Elderly Chinese
J. Nutr., December 1, 2008; 138(12): 2413 - 2421.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
Y. Kokubo, H. Iso, J. Ishihara, K. Okada, M. Inoue, S. Tsugane, and for the JPHC Study Group
Association of Dietary Intake of Soy, Beans, and Isoflavones With Risk of Cerebral and Myocardial Infarctions in Japanese Populations: The Japan Public Health Center Based (JPHC) Study Cohort I
Circulation, November 27, 2007; 116(22): 2553 - 2562.
[Abstract] [Full Text] [PDF]


Home page
Int J EpidemiolHome page
T. Shimazu, S. Kuriyama, A. Hozawa, K. Ohmori, Y. Sato, N. Nakaya, Y. Nishino, Y. Tsubono, and I. Tsuji
Dietary patterns and cardiovascular disease mortality in Japan: a prospective cohort study
Int. J. Epidemiol., June 1, 2007; 36(3): 600 - 609.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
P. Zhang, W. Kim, L. Zhou, N. Wang, L. H. Ly, D. N. McMurray, and R. S. Chapkin
Dietary Fish Oil Inhibits Antigen-Specific Murine Th1 Cell Development by Suppression of Clonal Expansion
J. Nutr., September 1, 2006; 136(9): 2391 - 2398.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
C. Wang, W. S Harris, M. Chung, A. H Lichtenstein, E. M Balk, B. Kupelnick, H. S Jordan, and J. Lau
n-3 Fatty acids from fish or fish-oil supplements, but not {alpha}-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: a systematic review
Am. J. Clinical Nutrition, July 1, 2006; 84(1): 5 - 17.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
J.A. Iestra, D. Kromhout, Y.T. van der Schouw, D.E. Grobbee, H.C. Boshuizen, and W.A. van Staveren
Effect Size Estimates of Lifestyle and Dietary Changes on All-Cause Mortality in Coronary Artery Disease Patients: A Systematic Review
Circulation, August 9, 2005; 112(6): 924 - 934.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
L. I Mennen, R. Walker, C. Bennetau-Pelissero, and A. Scalbert
Risks and safety of polyphenol consumption
Am. J. Clinical Nutrition, January 1, 2005; 81(1): 326S - 329S.
[Abstract] [Full Text] [PDF]


Home page
J. Immunol.Home page
Y.-Y. Fan, L. H. Ly, R. Barhoumi, D. N. McMurray, and R. S. Chapkin
Dietary Docosahexaenoic Acid Suppresses T Cell Protein Kinase C{theta} Lipid Raft Recruitment and IL-2 Production
J. Immunol., November 15, 2004; 173(10): 6151 - 6160.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
M. S Rosell, P. N Appleby, E. A Spencer, and T. J Key
Soy intake and blood cholesterol concentrations: a cross-sectional study of 1033 pre- and postmenopausal women in the Oxford arm of the European Prospective Investigation into Cancer and Nutrition
Am. J. Clinical Nutrition, November 1, 2004; 80(5): 1391 - 1396.
[Abstract] [Full Text] [PDF]


Home page
J. Lipid Res.Home page
K. C. Switzer, Y.-Y. Fan, N. Wang, D. N. McMurray, and R. S. Chapkin
Dietary n-3 polyunsaturated fatty acids promote activation-induced cell death in Th1-polarized murine CD4+ T-cells
J. Lipid Res., August 1, 2004; 45(8): 1482 - 1492.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
X. Zhang, X. O. Shu, Y.-T. Gao, G. Yang, Q. Li, H. Li, F. Jin, and W. Zheng
Soy Food Consumption Is Associated with Lower Risk of Coronary Heart Disease in Chinese Women
J. Nutr., September 1, 2003; 133(9): 2874 - 2878.
[Abstract] [Full Text] [PDF]



Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.