Am J Epidemiol 2002; 156:139-147.
Copyright © 2002 by the
Johns Hopkins Bloomberg School of Public Health
ORIGINAL CONTRIBUTIONS |
Physical Inactivity Is Associated with Lower Forced Expiratory Volume in 1 Second
European Prospective Investigation into Cancer-Norfolk Prospective Population Study
1 Department of Public Health and Primary Care, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge, CB2 2SR, England.
2 Department of Public Health and Primary Care, Strangeways Research Laboratory, Worts Causeway, Cambridge, CB1 8RN, England.
3 Dunn Human Nutrition Unit, Cambridge, CB2 2XY, England.
Forced expiratory volume in 1 second (FEV1) is a strong risk factor for cardiovascular disease, stroke, lung cancer, and all-cause mortality. One possible explanation for this association is that FEV1 is a marker of other determinants of mortality risk, such as obesity and physical inactivity. In a population-based cohort study of 12,283 men and women aged 4574 years from the European Prospective Investigation into Cancer-Norfolk Study recruited in 19931997, the cross-sectional association between physical activity and FEV1 and that between physical activity and change in FEV1 were analyzed. Indices of physical activity, including participation in vigorous recreational activity, stair climbing, and television viewing, were assessed with a validated questionnaire designed to assess activity in the previous year. Television viewing was negatively associated with FEV1 in men and women (p < 0.001), whereas stair climbing and participation in vigorous leisure time activities were positively associated with FEV1 in men and women (p < 0.001). The associations remained after adjustment for known confounders, including age, height, vitamin C, and smoking. Climbing more stairs and participating in vigorous leisure-time activity predicted a slower rate in annual percent decline in FEV1 (p < 0.004 and p < 0.002, respectively). In conclusion, physical activity is associated with higher levels of FEV1, whereas television viewing is associated with lower levels. Am J Epidemiol 2002;156:13947.
exercise; lung; television
Abbreviations: Abbreviations: EPAQ2, European Prospective Investigation into Cancer Physical Activity Questionnaire; EPIC, European Prospective Investigation into Cancer; FEV1, forced expiratory volume in 1 second; MET, metabolic equivalent.
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