American Journal of Epidemiology Vol. 155, No. 10 : 949-957
Copyright © 2002 by The Johns Hopkins University School of Hygiene and Public Health
ORIGINAL CONTRIBUTIONS |
Association of Sexual Activity with Colonization and Vaginal Acquisition of Group B Streptococcus in Nonpregnant Women
1 Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh, Pittsburgh, PA.
2 Magee-Womens Research Institute, Magee-Womens Hospital, University of Pittsburgh, Pittsburgh, PA.
In a longitudinal cohort study of 1,248 nonpregnant young women recruited from three Pittsburgh, Pennsylvania, health clinics in 1998–2000, the authors investigated risk factors associated with vaginal acquisition of group B Streptococcus (GBS). Rectal and vaginal swabs for GBS culture and demographic and behavioral interview data were obtained from the women at enrollment and at three 4-month intervals. Cox proportional hazards models were used to evaluate risk factors for GBS acquisition among the 1,089 women with follow-up data. At enrollment, 365 (29.2%) of the 1,248 study participants were vaginally colonized with GBS. Of 767 women who were GBS-negative at enrollment, 344 (44.9%) acquired vaginal GBS colonization during follow-up. The following factors were independently associated with vaginal acquisition of GBS at the 0.05 significance level: African-American race (hazard ratio (HR) = 1.5, 95% confidence interval (CI): 1.2, 1.9), having multiple sex partners during the past 4 months (HR = 1.7, 95% CI: 1.1, 2.5), having frequent sexual intercourse during the past 4 months (HR = 1.5, 95% CI: 1.1, 2.2), and having sexual intercourse within the 5 days prior to the follow-up visit (HR = 1.6, 95% CI: 1.3, 2.0). These results show that sexual activity is an important risk factor for vaginal acquisition of GBS.
regression analysis; risk factors; sex behavior; sexually transmitted diseases; streptococcal infections; Streptococcus agalactiae; vagina
Abbreviations: CI, confidence interval; CNA plates, Columbia agar plates containing 5 percent sheep blood, colistin, and nalidixic acid; GBS, group B Streptococcus; HR, hazard ratio; OR, odds ratio
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  G. R. Bolduc and L. C. Madoff The group B streptococcal alpha C protein binds {alpha}1 1-integrin through a novel KTD motif that promotes internalization of GBS within human epithelial cells Microbiology, December 1, 2007; 153(12): 4039 - 4049. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Foxman, B. Gillespie, S. D. Manning, L. J. Howard, P. Tallman, L. Zhang, and C. F. Marrs Incidence and Duration of Group B Streptococcus by Serotype among Male and Female College Students Living in a Single Dormitory Am. J. Epidemiol., March 15, 2006; 163(6): 544 - 551. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. D. Stapleton, J. M. Kahn, L. E. Evans, C. W. Critchlow, and C. M. Gardella Risk Factors for Group B Streptococcal Genitourinary Tract Colonization in Pregnant Women Obstet. Gynecol., December 1, 2005; 106(6): 1246 - 1252. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. M. Puopolo, L. C. Madoff, and E. C. Eichenwald Early-Onset Group B Streptococcal Disease in the Era of Maternal Screening Pediatrics, May 1, 2005; 115(5): 1240 - 1246. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. A. Stoner, L. K. Rabe, and S. L. Hillier Effect of Transport Time, Temperature, and Concentration on the Survival of Group B Streptococci in Amies Transport Medium J. Clin. Microbiol., November 1, 2004; 42(11): 5385 - 5387. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. H. Beigi, L. A. Meyn, D. M. Moore, M. A. Krohn, and S. L. Hillier Vaginal Yeast Colonization in Nonpregnant Women: A Longitudinal Study Obstet. Gynecol., November 1, 2004; 104(5): 926 - 930. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. S. Gibbs, S. Schrag, and A. Schuchat Perinatal Infections Due to Group B Streptococci Obstet. Gynecol., November 1, 2004; 104(5): 1062 - 1076. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Hansen, N. Uldbjerg, M. Kilian, and U. B. S. Sorensen Dynamics of Streptococcus agalactiae Colonization in Women during and after Pregnancy and in Their Infants J. Clin. Microbiol., January 1, 2004; 42(1): 83 - 89. [Abstract] [Full Text] [PDF]
|
|