American Journal of Epidemiology Vol. 154, No. 2 : 150-154
Copyright © 2001 by The Johns Hopkins University School of Hygiene and Public Health
ORIGINAL CONTRIBUTIONS |
Lifestyle Factors and Plasma Homocysteine Concentrations in a General Population Sample
1 Department of Chronic Disease Epidemiology, National Institute of Public Health and the Environment, Bilthoven, the Netherlands.
2 Laboratory of Pediatrics and Neurology, University Hospital, St. Radboud, the Netherlands.
The authors cross-sectionally investigated the extent to which coffee, tea, and alcohol consumption, physical activity, and smoking were associated with nonfasting total plasma homocysteine concentrations in a random sample of 3,025 Dutch adults aged 20–65 years from a population-based cohort examined in 1993–1996 (n = 19,066). The lifestyle factors most strongly associated with plasma total homocysteine level were smoking (positive), alcohol drinking (negative), and coffee consumption (positive). The smoking effect was most prominent in women, and the alcohol effect was most pronounced in men. Data indicated that independently of other lifestyle factors, age, and intake of folate and B vitamin supplements, a change in lifestyle could result in a 0.1- to 1.7-µmol/liter change in plasma total homocysteine level. The authors conclude that lifestyle changes could result in a public-health-relevant change in plasma total homocysteine concentrations.
adult; alcohol drinking; cardiovascular diseases; coffee; homocysteine; life style; smoking
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  J. H Holstein, M. Herrmann, C. Splett, W. Herrmann, P. Garcia, T. Histing, S. Graeber, M. F. Ong, K. Kurz, T. Siebel, et al. Low serum folate and vitamin B-6 are associated with an altered cancellous bone structure in humans Am. J. Clinical Nutrition, November 1, 2009; 90(5): 1440 - 1445. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. M. van Dam Coffee Consumption and Coronary Heart Disease: Paradoxical Effects on Biological Risk Factors versus Disease Incidence Clin. Chem., September 1, 2008; 54(9): 1418 - 1420. [Full Text] [PDF]
|
|
|
|
 |
|
 S. K. Park, M. S. O'Neill, P. S. Vokonas, D. Sparrow, A. Spiro III, K. L. Tucker, H. Suh, H. Hu, and J. Schwartz Traffic-related Particles Are Associated with Elevated Homocysteine: The VA Normative Aging Study Am. J. Respir. Crit. Care Med., August 1, 2008; 178(3): 283 - 289. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. H Halsted, D. H Wong, J. M Peerson, C. H Warden, H. Refsum, A D. Smith, O. K Nygard, P. M Ueland, S. E Vollset, and G. S Tell Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: the Hordaland Homocysteine Study Am. J. Clinical Nutrition, August 1, 2007; 86(2): 514 - 521. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Refsum, E. Nurk, A. D. Smith, P. M. Ueland, C. G. Gjesdal, I. Bjelland, A. Tverdal, G. S. Tell, O. Nygard, and S. E. Vollset The Hordaland Homocysteine Study: A Community-Based Study of Homocysteine, Its Determinants, and Associations with Disease J. Nutr., June 1, 2006; 136(6): 1731S - 1740S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. E Chiuve, E. L Giovannucci, S. E Hankinson, D. J Hunter, M. J Stampfer, W. C Willett, and E. B Rimm Alcohol intake and methylenetetrahydrofolate reductase polymorphism modify the relation of folate intake to plasma homocysteine Am. J. Clinical Nutrition, July 1, 2005; 82(1): 155 - 162. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Auer, G. Lamm, B. Eber, M. Bursztyn, J. L. Perez-Castrillon, M. L. Arranz-Pena, D. D. Luis, S. S. Ellenberg, D. G. Orloff, R. J. Temple, et al. Homocysteine as a Predictive Factor for Hip Fracture in Older Persons N. Engl. J. Med., September 2, 2004; 351(10): 1027 - 1030. [Full Text] [PDF]
|
|
|
|
|
|
E. Nurk, G. S Tell, S. E Vollset, O. Nygard, H. Refsum, R. M Nilsen, and P. M Ueland Changes in lifestyle and plasma total homocysteine: the Hordaland Homocysteine Study Am. J. Clinical Nutrition, May 1, 2004; 79(5): 812 - 819. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Refsum, A. D. Smith, P. M. Ueland, E. Nexo, R. Clarke, J. McPartlin, C. Johnston, F. Engbaek, J. Schneede, C. McPartlin, et al. Facts and Recommendations about Total Homocysteine Determinations: An Expert Opinion Clin. Chem., January 1, 2004; 50(1): 3 - 32. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Tsiara, M. Elisaf, and D. P. Mikhailidis Influence of Smoking on Predictors of Vascular Disease Angiology, September 1, 2003; 54(5): 507 - 530. [Abstract] [PDF]
|
|
|
|
|
|
C. Infante-Rivard, G.-E. Rivard, R. Gauthier, and Y. Theoret Unexpected Relationship between Plasma Homocysteine and Intrauterine Growth Restriction Clin. Chem., September 1, 2003; 49(9): 1476 - 1482. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. I Mennen, G. P. de Courcy, J.-C. Guilland, V. Ducros, M. Zarebska, S. Bertrais, A. Favier, S. Hercberg, and P. Galan Relation between homocysteine concentrations and the consumption of different types of alcoholic beverages: the French Supplementation with Antioxidant Vitamins and Minerals Study Am. J. Clinical Nutrition, August 1, 2003; 78(2): 334 - 338. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. A. Bazzano, J. He, P. Muntner, S. Vupputuri, and P. K. Whelton Relationship between Cigarette Smoking and Novel Risk Factors for Cardiovascular Disease in the United States Ann Intern Med, June 3, 2003; 138(11): 891 - 897. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Ganji and M. R Kafai Demographic, health, lifestyle, and blood vitamin determinants of serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey, 1988-1994 Am. J. Clinical Nutrition, April 1, 2003; 77(4): 826 - 833. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M Hodgson, V. Burke, L. J Beilin, K. D Croft, and I. B Puddey Can black tea influence plasma total homocysteine concentrations? Am. J. Clinical Nutrition, April 1, 2003; 77(4): 907 - 911. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Nagata, H. Shimizu, R. Takami, M. Hayashi, N. Takeda, and K. Yasuda Soy Product Intake Is Inversely Associated with Serum Homocysteine Level in Premenopausal Japanese Women J. Nutr., March 1, 2003; 133(3): 797 - 800. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. De Bree, W. M. M. Verschuren, D. Kromhout, L. A. J. Kluijtmans, and H. J. Blom Homocysteine Determinants and the Evidence to What Extent Homocysteine Determines the Risk of Coronary Heart Disease Pharmacol. Rev., December 1, 2002; 54(4): 599 - 618. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. P. Agarwal CARDIOPROTECTIVE EFFECTS OF LIGHT-MODERATE CONSUMPTION OF ALCOHOL: A REVIEW OF PUTATIVE MECHANISMS Alcohol Alcohol., September 1, 2002; 37(5): 409 - 415. [Abstract] [Full Text] [PDF]
|
|