American Journal of Epidemiology Vol. 154, No. 10 : 924-933
Copyright © 2001 by The Johns Hopkins University School of Hygiene and Public Health
ORIGINAL CONTRIBUTIONS |
Recreational Physical Activity and Endometrial Cancer Risk
1 Department of Epidemiology, University of Washington, Seattle, WA.
2 Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA.
To investigate the association between recreational physical activity and endometrial cancer risk, a population-based case-control study was conducted in Washington State. The study included 822 incident cases of endometrial cancer diagnosed between 1985 and 1991 and 1,111 randomly selected population-based controls. Detailed information on recreational physical activities as well as other endometrial cancer risk factors was obtained in structured, in-person interviews. Unconditional logistic regression, adjusted for age, county, energy intake, unopposed estrogen use, income, and, in separate models, body mass index (kg/m2), was used to estimate the odds ratios and their 95% confidence intervals, relating endometrial cancer to each level of physical activity. A greater proportion of controls (49.3%) than cases (40.5%) reported doing regular exercise (compared with no exercise: adjusted odds ratio = 0.62, 95% confidence interval: 0.51, 0.76) in the 2-year period prior to diagnosis date. There was little evidence of a trend of decreasing risk with increasing duration or intensity of recreational physical activities. These results provide support for an association between the lack of recent recreational physical activity and endometrial cancer risk. However, the absence of a difference by duration or intensity levels and the inconsistent results from other studies suggest caution before interpreting this association as causal.
case-control studies; endometrial neoplasms; exercise; physical fitness; risk factors
Abbreviations: CI, confidence interval; MET, metabolic equivalent; OR, odds ratio
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  A. Samat, A. Rahim, and A. Barnett Pharmacotherapy for obesity in menopausal women Menopause Int, June 1, 2008; 14(2): 57 - 62. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. W. Voskuil, E. M. Monninkhof, S. G. Elias, F. A. Vlems, F. E. van Leeuwen, and Task Force Physical Activity and Cancer Physical Activity and Endometrial Cancer Risk, a Systematic Review of Current Evidence Cancer Epidemiol. Biomarkers Prev., April 1, 2007; 16(4): 639 - 648. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Friberg, C. S. Mantzoros, and A. Wolk Physical Activity and Risk of Endometrial Cancer: A Population-Based Prospective Cohort Study Cancer Epidemiol. Biomarkers Prev., November 1, 2006; 15(11): 2136 - 2140. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Schnohr, M. Gronbaek, L. Petersen, H. Ole Hein, and T. Ia Sorensen Physical activity in leisure-time and risk of cancer: 14-year follow-up of 28,000 Danish men and women Scand J Public Health, August 1, 2005; 33(4): 244 - 249. [Abstract] [PDF]
|
|
|
|
|
|
C. E. Matthews, W. H. Xu, W. Zheng, Y. T. Gao, Z. X. Ruan, J. R. Cheng, Y. B. Xiang, and X. O. Shu Physical Activity and Risk of Endometrial Cancer: A Report from the Shanghai Endometrial Cancer Study Cancer Epidemiol. Biomarkers Prev., April 1, 2005; 14(4): 779 - 785. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. K. Dhillon and V. L. Holt Recreational Physical Activity and Endometrioma Risk Am. J. Epidemiol., July 15, 2003; 158(2): 156 - 164. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. M. Friedenreich and M. R. Orenstein Physical Activity and Cancer Prevention: Etiologic Evidence and Biological Mechanisms J. Nutr., November 1, 2002; 132(11): 3456S - 3464. [Abstract] [Full Text] [PDF]
|
|