American Journal of Epidemiology, Vol 152, Issue 9 855-862, Copyright © 2000 by Oxford University Press
EC Lau, C Cooper, D Lam, VN Chan, KK Tsang and A Sham
In 1998, a case-control study was conducted in Hong Kong on hospital
patients with osteoarthritis of the hip (n = 138) and osteoarthritis of the
knee (n = 658). Age- and sex-matched controls were recruited consecutively
from general practice clinics in the same region. The following three risk
factors were found to be associated with osteoarthritis of both the hip and
the knee: first, a history of joint injury: for osteoarthritis of the hip,
the odds ratio = 25.1 (95% confidence interval (CI): 3.5, 181) in men and
43.3 (95% CI: 11.7, 161) in women; for osteoarthritis of the knee, the odds
ratio = 12.1 (95% CI: 3.4, 42.5) in men and 7.6 (95% CI: 3.8, 15.2) in
women; second, climbing stairs frequently: for osteoarthritis of the hip,
the odds ratio = 12.5 (95% CI: 1.5, 104.3) in men and 2.3 (95% CI: 0.6,
8.1) in women; for osteoarthritis of the knee, the odds ratio = 2.5 (95%
CI: 1.0, 6.4) in men and 5.1 (95% CI: 2.5, 10.2) in women; third, lifting
heavy weight frequently: for osteoarthritis of the hip, the odds ratio =
3.1 (95% CI: 0.7, 14.3) in men and 2.4 (95% CI: 1.1, 5.3) in women; for
osteoarthritis of the knee, the odds ratio = 5.4 (95% CI: 2.4, 12.4) in men
and 2.0 (95% CI: 1.2, 3.1) in women. In addition, subjects whose height and
weight were in the highest quartile were at increased risk of
osteoarthritis of the hip and knee, respectively (p < 0.05).
Factors associated with osteoarthritis of the hip and knee in Hong Kong Chinese: obesity, joint injury, and occupational activities [In Process Citation]
Department of Community and Family Medicine, The Chinese University of Hong Kong. edithlau@cuhk.edu.hk
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