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American Journal of Epidemiology Vol. 152, No. 11 : 1034-1038
Copyright © 2000 by The Johns Hopkins University School of Hygiene and Public Health

ORIGINAL CONTRIBUTIONS

Association of Coffee Consumption with Gallbladder Disease

Constance E. Ruhl1 and James E. Everhart2

1 Social and Scientific Systems, Inc., Bethesda, MD.
2 National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

Coffee consumption was recently shown to protect against symptomatic gallbladder disease in men. The authors examined the relation of ultrasound-documented gallbladder disease with coffee drinking in 13,938 adult participants in the Third National Health and Nutrition Examination Survey, 1988–1994. The prevalence of total gallbladder disease was unrelated to coffee consumption in either men or women. However, among women a decreased prevalence of previously diagnosed gallbladder disease was found with increasing coffee drinking (p = 0.027). These findings do not support a protective effect of coffee consumption on total gallbladder disease, although coffee may decrease the risk of symptomatic gallstones in women.

cholelithiasis; coffee; gallbladder diseases; nutrition surveys; risk factors

Abbreviations: NHANES III, Third National Health and Nutrition Examination Survey.


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