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American Journal of Epidemiology Vol. 149, No. 2: 162-167
Copyright © 1999 by The Johns Hopkins University School of Hygiene and Public Health


other

Coffee and Tea Intake and the Risk of Myocardial Infarction

Howard D. Sesso1,2, J. Michael Gaziano1,3,4, Julie E. Buring1,2,5 and Charles H. Hennekens1,2,5

1 Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School Boston, MA
2 Department of Epidemiology, Harvard School of Public Health Boston, MA
3 Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School Boston, MA
4 Massachusetts Veterans Epidemiology Research and Information Center, Veterans Affairs Medical Center Brockton/West Roxbury, MA
5 Department of Ambulatory Care and Prevention, Harvard Medical School Boston, MA

Reprint requests to Dr. Howard D. Sesso, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, MA 02215.

The authors investigated the association of caffeinated coffee, decaffeinated coffee, and tea with myocardial infarction in a study of 340 cases and age-, sex-, and community-matched controls. The odds ratio for drinking >=4 cups/day of caffeinated coffee versus drinking <=1 cup/week was 0.84 (95% confidence interval (CI) 0.49–1.42) after adjustment for coronary risk factors (1 cup = 237 ml). The odds ratio for drinking >1 cup/day of decaffeinated coffee versus nondrinkers was 1.25 (95% CI 0.76–2.04). For tea, the odds ratio for drinking >=1 cup/day versus nondrinkers was 0.56 (95% CI 0.35–0.90). In these data, only tea was associated with a lower risk of myocardial infarction. Am J Epidemiol 1999;149:162–7.

caffeine; case-control studies; coffee; flavones; myocardial infarction; tea


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