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American Journal of Epidemiology Vol. 147, No. 4: 353-361
Copyright © 1998 by The Johns Hopkins University School of Hygiene and Public Health


research-article

Risk Factors for DSM-III-R Posttraumatic Stress Disorder: Findings from the National Comorbidity Survey

Evelyn Bromet1,, Amanda Sonnega2 and Ronald C. Kessler3

1Department of Psychiatry and Behavioral Science, School of Medicine, State University of New York Stony Brook, NY
2Institute for Scial Research, University of Michigan Ann Arbor, Ml
3Department of Health Care Policy, Harvard Medical School Cambridge, MA

Reprint requests to Dr. Evelyn Bromet, Department of Phychiatry, State University of New York at Stony Brook, Pitnam Hall-south Campus, Stony Brook, NY 11794-8790.

The present study examined the association of childhood risk factors with exposure to traumas and posttraumatic stress disorder (PTSD). PTSD is a unique symptom configuration after exposure to an unusual, extreme event. Data come from the US National Comorbidity Study of 5,877 respondents aged 15–54 years conducted between September 1990 and February 1992. The risk factors examined were preexposure affective, anxiety, and substance use disorders; parental mental and substance use disorders; parental aggression toward the respondent and toward the other parent; and a nonconfiding relationship with the mother during childhood. Analyses were stratified by gender and adjusted for demographic variables and traumatic experiences prior to the index trauma. The occurrence of trauma was associated with many risk factors in women but few in men. Similarly, more risk factors predicted PTSD in women than in men. Overall, when respondents were grouped into broad trauma categories, an increase in the number of risk factors was associated with higher rates of PTSD. However, in analyses of the trauma subsample that adjusted for individual type of trauma (e.g., rape, physical attack), only one risk factor (history of affective disorder) predicted PTSD in women, and two (history of anxiety disorder and parental mental disorder) predicted PTSD in men. The results thus indicate that although these risk factors have an important association with PTSD, they operate largely by predicting trauma exposure rather than by predicting the onset of disorder after exposure. Am J Epidemiol 1998; 147: 353–61.

affective disorders; aggression; anxiety disorders; mental disorders; stress disorders; post-traumatic; substance use disorder; trauma


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