American Journal of Epidemiology Vol. 145, No. 2: 117-123
Copyright © 1997 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
Dietary Factors and the Incidence of Hip Fracture in Middle-aged Norwegians
A Prospective Study
1National Health Screening Service P.O. Box 8155 Dep., 0033 Oslo, Norway
2Institute for Nutrition Research, University of Oslo P.O. Box 1046 Blindern, 0316 Oslo, Norway
Reprint requests to Dr. Haakon E. Meyer, National Health Screening Service, Storgata 33 A, P.O. Box 8155 Dep., N-0033 Oslo, Norway.
Dietary data from a prospective study were used to relate factors influencing calcium balance (estimates of dietary calcium intake, protein intake from nondairy animal sources (meat, fish, and eggs), and coffee consumption) to the incidence of hip fracture. During the years 1977–1983, women and men bom between 1925 and 1940 and living in one of three Norwegian counties were invited to a cardiovascular screening that included a dietary survey. The attendance rate at screening was 91.1 %, and 90.7% of these persons (19,752 women and 20,035 men) filled in and returned a semiquantitative dietary questionnaire. This cohort was followed for an average of 11.4 years (range, 0.01–13.8 years) with respect to hip fracture, defined as cervical or trochanteric fracture. During follow-up, 213 hip fractures were identified, excluding fractures associated with high-energy trauma and metastatic bone disease. There was no clear association between calcium intake or nondairy animal protein intake and hip fracture in this cohort. However, an elevated risk of fracture was found in women with a high intake of protein from nondairy animal sources in the presence of low calcium intake (relative risk = 1.96 (95% confidence interval 1.09–3.56) for the highest quarter of nondairy protein intake and the lowest quarter of calcium intake vs. the three lower quarters of protein intake and the three higher quarters of calcium intake). Women who drank nine or more cups of coffee per day also had an increased risk of fracture, while there was no association between coffee consumption and hip fracture in men. Although these findings do not necessarily imply causal relations, they suggest the presence of risk factors for hip fracture that act through a negative calcium balance in this population. Am J Epidemiol 1997; 145: 117–23.
calcium, dietary; coffee; dietary proteins; hip fractures; longitudinal studies; nutrition
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  A. L Darling, D J. Millward, D. J Torgerson, C. E Hewitt, and S. A Lanham-New Dietary protein and bone health: a systematic review and meta-analysis Am. J. Clinical Nutrition, December 1, 2009; 90(6): 1674 - 1692. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W.-P. Koh, A. H. Wu, R. Wang, L.-W. Ang, D. Heng, J.-M. Yuan, and M. C. Yu Gender-specific Associations Between Soy and Risk of Hip Fracture in the Singapore Chinese Health Study Am. J. Epidemiol., October 1, 2009; 170(7): 901 - 909. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. P. Heaney Dairy and Bone Health J. Am. Coll. Nutr., February 1, 2009; 28(Supplement_1): 82S - 90S. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Vatanparast, D. A. Bailey, A. D. G. Baxter-Jones, and S. J. Whiting The Effects of Dietary Protein on Bone Mineral Mass in Young Adults May Be Modulated by Adolescent Calcium Intake J. Nutr., December 1, 2007; 137(12): 2674 - 2679. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-P. Bonjour Dietary Protein: An Essential Nutrient For Bone Health J. Am. Coll. Nutr., December 1, 2005; 24(suppl_6): 526S - 536S. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. R. Zwart, J. E. Davis-Street, D. Paddon-Jones, A. A. Ferrando, R. R. Wolfe, and S. M. Smith Amino acid supplementation alters bone metabolism during simulated weightlessness J Appl Physiol, July 1, 2005; 99(1): 134 - 140. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. K. Roughead, J. R. Hunt, L. K. Johnson, T. M. Badger, and G. I. Lykken Controlled Substitution of Soy Protein for Meat Protein: Effects on Calcium Retention, Bone, and Cardiovascular Health Indices in Postmenopausal Women J. Clin. Endocrinol. Metab., January 1, 2005; 90(1): 181 - 189. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. R Zwart, A. R Hargens, and S. M Smith The ratio of animal protein intake to potassium intake is a predictor of bone resorption in space flight analogues and in ambulatory subjects Am. J. Clinical Nutrition, October 1, 2004; 80(4): 1058 - 1065. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Bowen, M. Noakes, and P. M. Clifton A High Dairy Protein, High-Calcium Diet Minimizes Bone Turnover in Overweight Adults during Weight Loss J. Nutr., March 1, 2004; 134(3): 568 - 573. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E Kerstetter, K. O O'Brien, and K. L Insogna Dietary protein, calcium metabolism, and skeletal homeostasis revisited Am. J. Clinical Nutrition, September 1, 2003; 78(3): 584S - 592. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. B Rapuri, J C. Gallagher, and V. Haynatzka Protein intake: effects on bone mineral density and the rate of bone loss in elderly women Am. J. Clinical Nutrition, June 1, 2003; 77(6): 1517 - 1525. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Dawson-Hughes Interaction of Dietary Calcium and Protein in Bone Health in Humans J. Nutr., March 1, 2003; 133(3): 852S - 854. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Kerstetter, K. O. O'Brien, and K. L. Insogna Low Protein Intake: The Impact on Calcium and Bone Homeostasis in Humans J. Nutr., March 1, 2003; 133(3): 855S - 861. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Feskanich, W. C Willett, and G. A Colditz Calcium, vitamin D, milk consumption, and hip fractures: a prospective study among postmenopausal women Am. J. Clinical Nutrition, February 1, 2003; 77(2): 504 - 511. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Ribeiro-Alves, L. C. Trugo, and C. M. Donangelo Use of Oral Contraceptives Blunts the Calciuric Effect of Caffeine in Young Adult Women J. Nutr., February 1, 2003; 133(2): 393 - 398. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Dawson-Hughes and S. S Harris Calcium intake influences the association of protein intake with rates of bone loss in elderly men and women Am. J. Clinical Nutrition, April 1, 2002; 75(4): 773 - 779. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. H. E. Promislow, D. Goodman-Gruen, D. J. Slymen, and E. Barrett-Connor Protein Consumption and Bone Mineral Density in the Elderly : The Rancho Bernardo Study Am. J. Epidemiol., April 1, 2002; 155(7): 636 - 644. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. B Rapuri, J C. Gallagher, H K. Kinyamu, and K. L Ryschon Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes Am. J. Clinical Nutrition, November 1, 2001; 74(5): 694 - 700. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. E Sellmeyer, K. L Stone, A. Sebastian, and S. R Cummings A high ratio of dietary animal to vegetable protein increases the rate of bone loss and the risk of fracture in postmenopausal women Am. J. Clinical Nutrition, January 1, 2001; 73(1): 118 - 122. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Z. Ilich and J. E. Kerstetter Nutrition in Bone Health Revisited: A Story Beyond Calcium J. Am. Coll. Nutr., June 1, 2000; 19(6): 715 - 737. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Kerstetter, M. E. Mitnick, C. M. Gundberg, D. M. Caseria, A. F. Ellison, T. O. Carpenter, and K. L. Insogna Changes in Bone Turnover in Young Women Consuming Different Levels of Dietary Protein J. Clin. Endocrinol. Metab., March 1, 1999; 84(3): 1052 - 1055. [Abstract] [Full Text]
|
|