American Journal of Epidemiology Vol. 145, No. 12: 1100-1105
Copyright © 1997 by The Johns Hopkins University School of Hygiene and Public Health
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Prognostic Factors and Survival of Laryngeal Cancer Patients from Turin, Italy: A Population-based Study
1Unit of Environmental Cancer Epidemiology, International Agency for Research on Cancer Lyon, France
2Department of MedicaJ Sciences, Novara Medical School No-vara, Italy
3Department of Community Medicine, School of Medicine, University of Turin, Turin, Italy
4Epidemiology Unit, Piedmont Cancer Registry Turin, Italy
5Unit of Cancer Epidemiology, School of Medicine, University of Turin Turin, Italy
Reprint requests to Dr. Paolo Boffetta, International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon cedex 08, France.
Little information is available on the role of risk factors for cancer of the larynx in survival. This study analyzed survival through the end of 1994 for 355 cases of laryngeal cancer diagnosed among residents of Turin, Italy, during 19791982. Relative survival at 5 years was 75% in women and 67% in men. The role of clinical and etiologic factors was analyzed in detail among 222 male cases. The role of nodal involvement as a strong predictor of poor survival was confirmed. Patients of low socioeconomic status experienced poorer survival than other patients, as did heavy smokers. Alcohol drinking and diet did not seem to strongly influence survival. Survival in this series of laryngeal cancer cases closely parallels that observed in other case series from Europe. While the results regarding socioeconomic status, tobacco smoking, and alcohol drinking parallel those of the few previous studies available, this investigation did not confirm a role for diet in the survival of laryngeal cancer patients, a finding that was recently seen in another study from northern Italy. Am J Epidemiol 1997; 145: 1100-5.
alcohol drinking; diet; laryngeal neoplasms; smoking; survival
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