| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
American Journal of Epidemiology Vol. 144, No. 2: 192-197
Copyright © 1996 by The Johns Hopkins University School of Hygiene and Public Health
other |
Optimizing Power in Allocating Resources to Exposure Assessment in an Epidemiologic Study
From the Department of Occupational Health, McGill University, Montreal, Quebec, Canada
Reprint requests to Dr. B. Armstrong, Environmental Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England (current address).
We consider an epidemiologic study with a fixed budget, in which resources may be put into increasing sample size or into improving accuracy of exposure assessments. To maximize study power (efficiency), improving accuracy is preferable if and only if the proportional increase in the square of the validity coefficient is more than the proportional increase in total study costs per subject that is required to achieve it. (The validity coefficient is the correlation between the true exposure and the approximate assessment in the study base.) This is most likely to be so if the cost of exposure measurement remains a small proportion of the overall costs per subject. The design with maximum power will not generally have minimum bias in measure of effect, so that alternative optimality criteria are required if this bias is important. Am J Epidemiol 1996; 144: 192–7.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  I. BURSTYN, H-M. KIM, N. CHERRY, and Y. YASUI Metamodels of bias in Cox proportional-hazards and logistic regressions with heteroscedastic measurement error under group-level exposure assessment Ann. Hyg., April 1, 2006; 50(3): 271 - 279. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S Kaur, M J Nieuwenhuijsen, H Ferrier, and P Steer Exposure of pregnant women to tap water related activities Occup. Environ. Med., May 1, 2004; 61(5): 454 - 460. [Abstract] [Full Text] [PDF]
|
|