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American Journal of Epidemiology Vol. 143, No. 5: 423-430
Copyright © 1996 by The Johns Hopkins University School of Hygiene and Public Health


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Evaporative Cooling and Other Home Factors and Lower Respiratory Tract Illness during the First Year of Life

Michael B. Aldous1,3,, Catharine J. Holberg2, Anne L. Wright1,2,3, Fernando D. Martinez1,2,3, Lynn M. Taussig1,2,3,4 and Group Health Medical Associates 5

1Department of Pediatrics, University of Arizona College of Medicine Tucson, AZ.
2Respiratory Sciences Center, University of Arizona College of Medicine Tucson, AZ.
3Steele Memorial Children's Research Center, University of Arizona College of Medicine Tucson, AZ.
4Presently with the National Jewish Center for Immunology and Respiratory Medicine Denver, CO.

Reprint requests to Dr. Michael B. Aldous, Department of Pediatrics, University of Arizona College of Medicine, 1501 N. Campbell Avenue, Tucson, AZ 85724.

Lower respiratory tract illness (LRI) is associated with exposure to various environmental factors. The relation between home environment and LRI in infants was studied with the use of data from the Children's Respiratory Study in Tucson, Arizona. Healthy infants from a health maintenance organization were recruited at birth (1980–1984). Analysis was restricted to one infant per family, and to those followed through the first year (n = 936). Environmental data were collected at enrollment, and clinicians diagnosed LRI according to predetermined criteria. During the first year of life, 196 infants (21%) had wheezing LRI, and 60 (6%) had nonwheezing LRI. The risk of wheezing LRI was higher in infants with evaporative home cooling (24%) than in those without evaporative home cooling (15%) (odds ratio = 1.8, 95% confidence interval 1.1–3.0); this association was stronger among infants who lived with other children in the home. The risk of nonwheezing LRI was associated with parents' rating of neighborhood dustiness, ranging from 5% in the least dusty environments to 12% in the dustiest (p for trend = 0.002). Neither association could be explained by confounding factors. LRI was not related to the type of home heating, cooking fuel, or the numbers of indoor dogs or cats. Am J Epidemiol 1996; 143:423–30.

air conditioning; air pollution; indoor; cats; dogs; dust; cooling; evaporative; infant; longitudinal studies; respiratory tract infections


5Group Health Medical Associates include Drs. John Bean, Henry Bianchi, John Curtiss, John Ey, Robert Moss, James Rothschild, Alejandro Sanguineti, Barbara Smith, Terry Vondrak, and Neil West, and Ms. Maureen McLellan, RN, PNP.


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