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American Journal of Epidemiology Vol. 142, No. 2: 176-182
Copyright © 1995 by The Johns Hopkins University School of Hygiene and Public Health

other

Longitudinal Compliance with Annual Screening for Fecal Occult Blood

William Thomas1, Christine M. White2, Jeng Mah2, Mindy S. Geisser2, Timothy R. Church2 and Jack S. Mandel2,

Minnesota Colon Cancer Control Study
1Division of Biostatistics, School of Public Health, University of Minnesota Minneapolis, MN.
2Division of Environmental and Occupational Health, School of Public Health, University of Minnesota Minneapolis, MN.

Reprint requests to Dr. Jack S. Mandel, Division of Environmental and Occupational Health, School of Public Health, University of Minnesota, Box 807, UMHC, 420 Delaware St. SE, Minneapolis, MN 55455.

In a randomized, controlled trial of fecal occult blood screening for colorectal cancer, the Minnesota Colon Cancer Control Study carried out 11 annual mail screens in two phases between 1976 and 1992. This long-term compliance record of 15,476 individuals is summarized and related to demographic characteristics as well as to the screening experience of the participants. There was a strong and consistent effect of age, with peak compliance among participants about 70 years old, and lower compliance among the youngest (≤55 years) and oldest (≥80 years) participants. There was a significantly higher rate of screen compliance among participants who lived with other participants, compared with households where only one individual participated in the study. Finally, participants who underwent a diagnostic colorectal examination with negative results had significantly lower odds of compliance.

colonic neoplasms; cooperative behavior; mass screening; prospective studies


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