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American Journal of Epidemiology Vol. 140, No. 4: 310-322
Copyright © 1994 by The Johns Hopkins University School of Hygiene and Public Health

research-article

Case-Control Study of Residential Radon and Lung Cancer in Winnipeg, Manitoba, Canada

E. G. Létourneau1,, D. Krewski1,2, N. W. Choi3,4, M. J. Goddard1, R. G. Mcgregor1, J. M Zielinski1 and J. Du3

1Health Protection Branch, Health Canada Ottawa, Ontario K1A 0L2, Canada
2Department of Mathematics and Statistics, Carleton University Ottawa, Ontario K1S 5B6, Canada
3Departrnent of Epidemiology and Biostatistics, Manitoba Cancer Treatment and Research Foundation, University of Manitoba Winnipeg, Manitoba R3E 0W9, Canada
4Department of Community Health Sciences, University of Manitoba Winnipeg, Manitoba R3E 0W9, Canada

Reprint requests to Dr. E. Létourneau, Radiation Protection Bureau, 775 Brookfield Road, Ottawa, Ontario K1A 1C1, Canada

A case-control study of lung cancer in relation to exposure to radon in homes in Winnipeg, Manitoba, Canada, was conducted during 1983–1990. In total, 738 individuals with histologically confirmed incident cases of lung cancer were interviewed, along with 738 controls matched on age (±5 years) and sex. Radon dosimeters were placed in all residences in which the study subjects had reported living within the Winnipeg metropolitan area for at least 1 year. Radon dosimetry was done by means of integrated alpha-track measurements over a 1-year period. In the homes monitored, the average level of radon-222 was about 120 becquerels (Bq)/m3 in the bedroom area and 200 Bq/m3 in the basement. After adjusting for cigarette smoking and education, no increase in the relative risk for any of the histologic types of lung cancer observed among the cases was detected in relation to cumulative exposure to radon.

confounding factors (epidemiology); logistic models; lung neoplasms; radon; regression analysis; relative risk; smoking


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