Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (56)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Jacqmin, H.
Right arrow Articles by Dartigues, J.-F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jacqmin, H.
Right arrow Articles by Dartigues, J.-F.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology Vol. 139, No. 1: 48-57
Copyright © 1994 by The Johns Hopkins University School of Hygiene and Public Health

research-article

Components of Drinking Water and Risk of Cognitive Impairment in the Elderly

Hèléne Jacqmin, Daniel Commenges, Luc Letenneur, Pascale Barberger-Gateau and Jean-François Dartigues

INSERM U330, Université de Bordeaux II, 146 rue Léo Saignat 33076 Bordeaux France

Reprint requests to Dr, Hèléne Jacqmin at this address.

The relation between aluminum, fluorine, calcium, and pH in drinking water and the risk for cognitive impairment was studied using data collected in 1988–1989 in a population-based survey of 3,777 French men and women aged 65 years and older (the Paquid study). Cognitive impairment was defined as a score lower than 24 on the Mini-Mental State Examination. Data related to drinking water came from two prospective measurement surveys whose reliability was checked by a variability study. A mixed effects logistic regression was performed, adjusting for the effects of the age, sex, educational level, and occupation of the participants. A significant protective effect was found for high calcium concentration (odds ratio = 0.8 for a concentration ≥75 mg vs. <75 mg, p = 0.015). For aluminum, no significant effect was found when pH was not Included in the model, but the results showed a weak interaction between aluminum and pH. When the four variables (calcium, aluminum, pH, and aluminum x pH interaction) were considered in the statistical analysis as a group, this group was significantly related to cognitive impairment (p = 0.01). Am J Epidemiol 1994;139:48–57.

aged; aging; aluminum; Alzheimer's disease; calcium; cognition disorders


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Journals of Gerontology Series A: Biological Sciences and Medical SciencesHome page
S. Gao, Y. Jin, F. W. Unverzagt, F. Ma, K. S. Hall, J. R. Murrell, Y. Cheng, J. Shen, B. Ying, R. Ji, et al.
Trace Element Levels and Cognitive Function in Rural Elderly Chinese
J. Gerontol. A Biol. Sci. Med. Sci., June 1, 2008; 63(6): 635 - 641.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
S. Gillette-Guyonnet, S. Andrieu, F. Nourhashemi, V. de La Gueronniere, H. Grandjean, and B. Vellas
Cognitive impairment and composition of drinking water in women: findings of the EPIDOS Study
Am. J. Clinical Nutrition, April 1, 2005; 81(4): 897 - 902.
[Abstract] [Full Text] [PDF]

Home page
 Am J EpidemiolHome page
V. Rondeau, D. Commenges, H. Jacqmin-Gadda, and J.-F. Dartigues
Relation between Aluminum Concentrations in Drinking Water and Alzheimer's Disease: An 8-year Follow-up Study
Am. J. Epidemiol., July 1, 2000; 152(1): 59 - 66.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
L. Zhu, L. Fratiglioni, Z. Guo, B. Winblad, and M. Viitanen
Incidence of stroke in relation to cognitive function and dementia in the Kungsholmen Project
Neurology, June 13, 2000; 54(11): 2103 - 2107.
[Abstract] [Full Text] [PDF]

Home page
 JAMAHome page
H. Jacqmin-Gadda, D. Commenges, and J.-F. Dartigues
Fluorine Concentration in Drinking Water and Fractures in the Elderly
JAMA, March 8, 1995; 273(10): 775 - 776.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.