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American Journal of Epidemiology Vol. 137, No. 12: 1376-1380
Copyright © 1993 by The Johns Hopkins University School of Hygiene and Public Health


research-article

Interpretation of Energy Adjustment Models for Nutritional Epidemiology

Victor Kipnis1,, Laurence S. Freedman1, Charles C. Brown1, Anne Hartman2, Arthur Schatzkin3 and Sholom Wacholder4

1Biometry Branch, Division of Cancer Prevention and Control, National Cancer Institute Bethesda, MD
2Applied Research Branch, Division of Cancer Prevention and Control, National Cancer Institute Bethesda, MD
3Cancer Prevention Studies Branch, Division of Cancer Prevention and Control, National Cancer Institute Bethesda, MD
4Biostatistics Branch, Division of Cancer Etiology, National Cancer Institute Bethesda, MD

Reprint requests to Dr. Victor Kipnis, Biometry Branch, Division of Cancer Prevention and Control, National Cancer Institute, Executive Plaza North, Suite 344, Bethesda, MD 20892

The authors discuss the interpretation of three alternative energy adjustment models for nutritional epidemiology. It is shown that four different effects are addressed by these models: 1) adding nutrient N, 2) substituting nutrient N for "other" nutrients, 3) adding "other" nutrients, and 4) adding both N and "other" nutrients in a specific ratio. Each of these effects may be estimated from any of the three models. The relative standard errors for the four estimated effects are also provided.

epidemiologic methods; models, statistical; nutrition


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