Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (43)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Haffner, S. M.
Right arrow Articles by Stem, M. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Haffner, S. M.
Right arrow Articles by Stem, M. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology Vol. 136, No. 9: 1060-1068
Copyright © 1992 by The Johns Hopkins University School of Hygiene and Public Health

research-article

Lipoprotein(a) Concentrations in Mexican Americans and Non-Hispanic Whites: The San Antonio Heart Study

Steven M. Haffner1,, Katherine K. Gruber1, Philip A. Morales1, Helen P. Hazuda1, Rodolfo A. Valdez1, Braxton D. Mitchell1 and Michael P. Stem1

1Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center at San Antonio San Antonio, TX

Reprint requests to Dr. Steven M Haffner, Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284–7873.

There is considerable evidence that lipoprotein(a) (Lp(a)) is a strong independent risk factor for coronary heart disease. Based on their risk factor profile, Mexican Americans have an increased risk of coronary heart disease, yet Mexican Americans have coronary heart disease mortality similar to or lower than that of non-Hispanic whites. The authors therefore attempted to determine whether Mexican Americans had decreased Lp(a) concentrations relative to non-Hispanic whites in the San Antonio Heart Study, a population-based study of diabetes and cardiovascular disease. Lp(a) concentrations (mg/dl) were significantly lower in Mexican Americans (n = 316) than in non-Hispanic whites (n =242) (men: 10. 4 vs. 16. 3; women: 11. 5 vs. 16. 4). In addition, the proportion of persons with Lp(a) concentrations of ≥30 mg/dl (the threshold at which increased risk of coronary heart disease is believed to occur) was significantly higher in non-Hispanic whites than in Mexican Americans (18. 6% vs. 7. 6%; Mantel-Haenszel odds ratio (adjusted for sex) = 2. 79). Age, obesity, body fat distribution, cigarette smoking, alcohol consumption, and glucose and insulin concentrations were not significantly related to Lp(a) levels. Decreased Lp(a) concentrations may account in part for Mexican Americans‘ relative protection from coronary heart disease mortality. Am J Epidemiol 1992; 136: 1060–8

coronary disease; diabetes mellitus; Hispanic Americans; lipoproteins


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
F. Paultre, C. H. Tuck, B. Boden-Albala, D. E. Kargman, E. Todd, J. Jones, M. C. Paik, R. L. Sacco, and L. Berglund
Relation of Apo(a) Size to Carotid Atherosclerosis in an Elderly Multiethnic Population
Arterioscler Thromb Vasc Biol, January 1, 2002; 22(1): 141 - 146.
[Abstract] [Full Text] [PDF]

Home page
 Vasc MedHome page
K. L Drowatzky, J L. Durstine, M. L Irwin, C. G Moore, P. G Davis, G. A Hand, M F. Gonzalez, and B. E Ainsworth
The association between physical activity, cardiorespiratory fitness, and lipoprotein(a) concentrations in a tri-ethnic sample of women: The Cross-Cultural Activity Participation Study
Vascular Medicine, February 1, 2001; 6(1): 15 - 21.
[Abstract] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
D. L. Rainwater and S. M. Haffner
Insulin and 2-Hour Glucose Levels Are Inversely Related to Lp(a) Concentrations Controlled for LPA Genotype
Arterioscler Thromb Vasc Biol, August 1, 1998; 18(8): 1335 - 1341.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
D. C. Goff, M. Z. Nichaman, W. Chan, D. J. Ramsey, D. R. Labarthe, and C. Ortiz
Greater Incidence of Hospitalized Myocardial Infarction Among Mexican Americans Than Non-Hispanic Whites : The Corpus Christi Heart Project, 1988-1992
Circulation, March 18, 1997; 95(6): 1433 - 1440.
[Abstract] [Full Text]

Home page
 StrokeHome page
D. Baldassarre, E. Tremoli, G. Franceschini, S. Michelagnoli, and C.R. Sirtori
Plasma Lipoprotein(a) Is an Independent Factor Associated With Carotid Wall Thickening in Severely but Not Moderately Hypercholesterolemic Patients
Stroke, June 1, 1996; 27(6): 1044 - 1049.
[Abstract] [Full Text]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
S. M. Haffner, C. Gonzalez, H. Miettinen, B. V. Howard, and M. P. Stern
LDL Size and Subclass Pattern in Mexico City Residents and San Antonio Mexican Americans
Arterioscler Thromb Vasc Biol, December 1, 1995; 15(12): 2136 - 2141.
[Abstract] [Full Text]

Home page
 CirculationHome page
R. L. Desmarais, I. J. Sarembock, C. R. Ayers, S. M. Vernon, E. R. Powers, and L. W. Gimple
Elevated Serum Lipoprotein(a) Is a Risk Factor for Clinical Recurrence After Coronary Balloon Angioplasty
Circulation, March 1, 1995; 91(5): 1403 - 1409.
[Abstract] [Full Text]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.