Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (22)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by IJsselmuiden, C. B.
Right arrow Articles by Comstock, G. W.
Right arrow Search for Related Content
PubMed
Right arrow Articles by IJsselmuiden, C. B.
Right arrow Articles by Comstock, G. W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology Vol. 136, No. 7: 836-842
Copyright © 1992 by The Johns Hopkins University School of Hygiene and Public Health

ORIGINAL CONTRIBUTIONS

Cancer of the Pancreas and Drinking Water: A Population-based Case-Control Study in Washington County, Maryland

Carel B. IJsselmuiden1, Charlotte Gaydos2, Brian Feighner3, William L. Novakoski4, David Serwadda5, Luis H. Caris6, David Vlahov7 and George W. Comstock7

1 Department of Community Health, Medical University of Southern Africa, MEDUNSA South Africa
2 Infectious Disease Division, Department of Medicine, The Johns Hopkins University Baltimore, MD
3 Walter Reed Army Institute of Research Washington, DC
4 Division of Preventive Medicine, Walter Reed Army Institute of Research Washington, DC
5 Makerere Medical School, Department of Medicine, Mulago Hospital Kampala, Uganda
6 School of Hygiene, University of Chile Independencia 929, Santiago, Chile
7 Department of Epidemiology, The Johns Hopkins University School of Hygiene and Public Health Baltimore, MD

Reprint requests to Dr. George W. Comstock, Training Center for Public Health Research, Box 2067, Hagerstown, MD 21742-2067

Received for publication August 12, 1991. Revision received July 7, 1992. A case-control study was done to assess a potential association between drinking water and pancreatic cancer in Washington County, Maryland. Cases of pancreatic cancer occurring from 1975 through 1989 were identified from the cancer registry. Controls were selected from the private 1975 census of Washington County. There were 101 cases and 206 controls. Chlorinated municipal water was used as a source of drinking water by 79% of cases and 63% of controls, yielding a significant odds ratio of 2.2. Adjustment for age and smoking had almost no effect on the risk, although both age and smoking were independently associated with an increased risk of pancreatic cancer. Although these findings must be interpreted with caution because of limitations in exposure assessment, these results have implications for the prevention of pancreatic cancer because chlorination of water is so widely practiced.

case-control studies; chlorine; pancreatic neoplasms; water supply


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Am J EpidemiolHome page
Honors and Awards * Bibliography of Peer-Reviewed Journal Articles
Am. J. Epidemiol., October 1, 2008; 168(7): 845 - 854.
[Full Text] [PDF]

Home page
 Am J EpidemiolHome page
K. Kasim, P. Levallois, K. C. Johnson, B. Abdous, P. Auger, and and the Canadian Cancer Registries Epidemiology Re
Chlorination Disinfection By-products in Drinking Water and the Risk of Adult Leukemia in Canada
Am. J. Epidemiol., January 15, 2006; 163(2): 116 - 126.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol Ind HealthHome page
G. L. Gist and J. A. R. Burg
Trichloroethylene -- a Review of the Literature From a Health Effects Perspective
Toxicology and Industrial Health, May 1, 1995; 11(3): 253 - 307.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.