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American Journal of Epidemiology Vol. 136, No. 10: 1175-1183
Copyright © 1992 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
Characteristics Relating to Ovarian Cancer Risk: Collaborative Analysis of 12 US Case-Control Studies
I. Methods
1Division of Epidemiology, Department of Health Research and Policy, Stanford University School of Medicine Stanford, CA
2Division of Biostatistics, Department of Health Research and Policy, Stanford University School of Medicine Stanford, CA
3Members of the Collaborative Ovanan Cancer Group' Dr. John T. Casagrande, Department of Preventive Medicine,University of Southern California, Los Angeles, CA, Dr. Daniel Cramer, Department of Obstetrics and Gynecotogy, Brigham and Women's Hospital, Boston, MA, Dr. Patricia Hartge, Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD; Dr. Jennifer L. Keisey, Division of Epidemiology, Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA; Dr. Manon Lee, Department of Epidemiology, University of California, San Francisco, San Francisco, CA; Dr. Nancy C. Lee, Women's Health and Fertility Branch, Division of Reproductive Health, Centers for Disease Control, Atlanta, GA; Dr Joseph L. Lyon, Department of Family and Community Medicine, The University of Utah Medical Center, Salt Lake City, UT, Dr. James R. Marshall, Department of Social and Preventive Medicine, State University of New York at Buffalo School of Medicine, Buffalo, New York; Dr Larry McGowan, Division of Gynecologic Oncology, Department of Obstetrics and Gynecdogy, George Washington University Medical Center, Washington, D. C , Dr Philip C. Nasca, New York State Department of Health, Bureau of Cancer Epidemiology, School of Pubic Health, Department of Epidemiology, Albany NY; Dr. Ralph S. Paffenbarger, Jr., Division of Epidemiology, Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA; Dr. Lynn Rosenberg, Slone Epidemiology Unit, School of Public Health, Boston University School of Medicine, Brookline, MA; and Dr. NoeJ S. Weiss, Department of Eptdemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA. Project Consultant: Dr. Genrose D. Copley, Extramural Programs, Division of Cancer Etiology, National Cancer Institute, Bethesda, MD.
Reprint requests to Dr. Alice S. Whittemore, Stanford University School of Medicine, Department of Health Research and Policy, HRP Modular no 2, Stanford, CA 94305–5092.
Data from 12 US case-control studies of ovarian cancer, conducted during the period 1956–1986 and representing some 3, 000 cases and 10,000 controls, were pooled and reanalyzed. Separate analyses were conducted for four subgroups of the pooled data: invasive epithelial ovarian cancers in white women; epithelial ovarian cancers of low malignant potential in white women, epithelial ovarian cancers in black women, and nonepithelial ovarian cancers. This paper gives a brief description of the participating studies and describes the methods used in the collaborative analysis. Am J Epidemiol1992; 136: 1175–83
case-control studies; methods; ovarian neoplasms
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