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American Journal of Epidemiology Vol. 135, No. 8: 854-864
Copyright © 1992 by The Johns Hopkins University School of Hygiene and Public Health


research-article

Myocardial Infarction and Coronary Death among Women: Psychosocial Predictors from a 20-Year Follow-up of Women in the Framingham Study

Elaine D. Eaker1,, Joan Pinsky2 and William P. Castelli3

1Epidemiology Program Office Division of Surveillance and Epidemiology Centers for Disease Control Atlanta, GA
2National Heart Lung and Blood Institute Bethesda MD
3Framingham Heart Study Framingham, MA

Reprint requests to Elaine D Eaker, Sc.D., Centers for Disease Control, Epidemiology Program Office, Division of Surveillance and Epidemiology, 1600 Clifton Road MS-C08, Atlanta GA 30333

This study investigates the relation of psychosocial variables to the 20-year incidence of myocardial infarction or coronary death among women in the Framingham Study In 1965–1967, a psychosocial interview was given along with the collection of other coronary risk factor data This study includes 749 women aged 45–64 years who were free of coronary disease at this baseline examination Demographic variables, psychosocial scales (such as tension and reactions of anger), and individual interview items (such as attitudes toward children, money, and religion) were measured When age, systolic blood pressure, the ratio of serum total cholesterol to high-density lipoprotein cholesterol, diabetes, cigarette smoking, and body mass index were controlled for in multivariate proportional hazards models, the predictors of the 20-year incidence of myocardial infarction or coronary death were as follows among employed women, perceived financial status only, among homemakers, symptoms of tension and anxiety, being lonely during the day, difficulty falling asleep, infrequent vacations, housework affecting health, and believing one is prone to heart disease (p < 0.05 for all variables), and among both groups of women combined, low educational level, tension, and lack of vacations These results are discussed in relation to previous findings from the Framingham Study. Am J Epidemiol 1992;135:854–64.

behavior; coronary disease; psychology; sociology; women


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