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American Journal of Epidemiology Vol. 135, No. 7: 769-774
Copyright © 1992 by The Johns Hopkins University School of Hygiene and Public Health


research-article

Body Mass Index and Lung Cancer Risk

Geoffrey C. Kabat and Ernst L. Wynder

From the Division of Epidemiology American Health Foundation New York NY

Reprint requests to Dr. Geoffrey C. Kabat, Division of Epidemiology, American Health Foundation, 320 East 43rd Street, New York, NY 10017.

The relation of body mass index, based on self-reported weight 5 years prior to diagnosis, to lung cancer was investigated in 3,607 lung cancer cases and 9,681 controls interviewed in a hospital-based case-control study in eight US cities between 1981 and 1990. Separate analyses were carried out by smoking status and by sex. After adjustment for covariates, odds ratios for lung cancer by levels of body mass index, taking ≥28 as the referent, showed an increasing linear trend with decreasing body mass index for current smokers and ex-smokers of both sexes and for female never smokers. These results are consistent with findings of a number of prospective studies. Further studies are needed to determine whether the association of tow body mass and lung cancer is due to factors associated with leanness or to a biologic effect of leanness itself. Am J Epidemiol 1992;135:769–74.

body mass index; diet; exercise; physical; lung neoplasms; smoking; weight loss


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