Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (66)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Seigel, D. G.
Right arrow Articles by Remaley, N. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Seigel, D. G.
Right arrow Articles by Remaley, N. A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology Vol. 135, No. 5: 571-578
Copyright © 1992 by The Johns Hopkins University School of Hygiene and Public Health

brief-report

Acceptable Values of Kappa for Comparison of Two Groups

Daniel G. Seigel, Marvin J. Podgo and Nancy A. Remaley

From the Biometry and Epidemiology Program, National Eye Institute, National Institutes of Health Bethesda, MD 20892

Reprint requests to Dr. Daniel G. Seigel, Building 31, Room 6A10, Biometry and Epidemiology Program, National Eye Institute, N1H, Bethesda, MD 20892

A model was developed for a simple clinical trial in which graders had defined probabilities of misclassifying pathologic material to disease present or absent. The authors compared Kappa between graders, and efficiency and bias in the clinical trial in the presence of misdassification. Though related to bias and efficiency, Kappa did not predict these two statistics well. These results pertain generally to evaluation of systems for encoding medical information, and the relevance of Kappa in determining whether such systems are ready for use in comparative studies. The authors conclude that, by itself, Kappa is not informative enough to evaluate the appropriateness of a grading scheme for comparative studies. Additional, and perhaps difficult, questions must be addressed for such evaluation.

bias; clinical trials; epidemiotogic methods; models, statistical; odds ratio; relative risk; statistics


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 BMJHome page
L. Hartling, M. Ospina, Y. Liang, D. M Dryden, N. Hooton, J. Krebs Seida, and T. P Klassen
Risk of bias versus quality assessment of randomised controlled trials: cross sectional study
BMJ, October 19, 2009; 339(oct19_1): b4012 - b4012.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
E. E. Spencer Jr, W. R. Dunn, R. W. Wright, B. R. Wolf, K. P. Spindler, E. McCarty, C. B. Ma, G. Jones, M. Safran, G. B. Holloway, et al.
Interobserver Agreement in the Classification of Rotator Cuff Tears Using Magnetic Resonance Imaging
Am. J. Sports Med., January 1, 2008; 36(1): 99 - 103.
[Abstract] [Full Text] [PDF]

Home page
 Ann OncolHome page
L Richiardi, D Mirabelli, R Calisti, A Ottino, A Ferrando, P Boffetta, and F Merletti
Occupational exposure to diesel exhausts and risk for lung cancer in a population-based case-control study in Italy
Ann. Onc., December 1, 2006; 17(12): 1842 - 1847.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
T. Herold, M. Bachthaler, O. W. Hamer, R. Hente, S. Feuerbach, C. Fellner, M. Strotzer, M. Lenhart, and C. Paetzel
Indirect MR Arthrography of the Shoulder: Use of Abduction and External Rotation to Detect Full- and Partial-Thickness Tears of the Supraspinatus Tendon
Radiology, July 1, 2006; 240(1): 152 - 160.
[Abstract] [Full Text] [PDF]

Home page
 AutismHome page
C. Receveur, P. Lenoir, H. Desombre, S. Roux, C. Barthelemy, and J. Malvy
Interaction and imitation deficits from infancy to 4 years of age in children with autism: A pilot study based on videotapes
Autism, February 1, 2005; 9(1): 69 - 82.
[Abstract] [PDF]

Home page
 J. Mol. Diagn.Home page
S. DeVries, S. Nyante, J. Korkola, R. Segraves, K. Nakao, D. Moore, H. Bae, M. Wilhelm, S. Hwang, and F. Waldman
Array-Based Comparative Genomic Hybridization from Formalin-Fixed, Paraffin-Embedded Breast Tumors
J. Mol. Diagn., February 1, 2005; 7(1): 65 - 71.
[Abstract] [Full Text] [PDF]

Home page
 Med Decis MakingHome page
J. K. Tobacman, I. U. Scott, S. T. Cyphert, and M. B. Zimmerman
Comparison of Appropriateness Ratings for Cataract Surgery between Convened and Mail-only Multidisciplinary Panels
Med Decis Making, December 1, 2001; 21(6): 490 - 497.
[Abstract] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
A. M. McCarthy, L. C. Richman, R. P. Hoffman, and L. Rubenstein
Psychological Screening of Children for Participation in Nontherapeutic Invasive Research
Arch Pediatr Adolesc Med, November 1, 2001; 155(11): 1197 - 1203.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
J.L. Anguenot, F. de Marval, P. Vassilakos, R. Auckenthaler, V. Ibecheole, and A. Campana
Combined screening for Chlamydia trachomatis and squamous intra-epithelial lesions using a single liquid-based cervical sample
Hum. Reprod., October 1, 2001; 16(10): 2206 - 2210.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Microbiol.Home page
I. Feder, J. C. Nietfeld, J. Galland, T. Yeary, J. M. Sargeant, R. Oberst, M. L. Tamplin, and J. B. Luchansky
Comparison of Cultivation and PCR-Hybridization for Detection of Salmonella in Porcine Fecal and Water Samples
J. Clin. Microbiol., July 1, 2001; 39(7): 2477 - 2484.
[Abstract] [Full Text] [PDF]

Home page
 Inj. Prev.Home page
D R Durbin, A R Localio, and E J MacKenzie
Validation of the ICD/AIS MAP for pediatric use
Inj. Prev., June 1, 2001; 7(2): 96 - 99.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
J. C. Grotta, D. Chiu, M. Lu, S. Patel, S. R. Levine, B. C. Tilley, T. G. Brott, E. C. Haley Jr, P. D. Lyden, R. Kothari, et al.
Agreement and Variability in the Interpretation of Early CT Changes in Stroke Patients Qualifying for Intravenous rtPA Therapy
Stroke, August 1, 1999; 30(8): 1528 - 1533.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.