American Journal of Epidemiology Vol. 134, No. 9: 923-937
Copyright © 1991 by The Johns Hopkins University School of Hygiene and Public Health
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Exposure to Residential Electric and Magnetic Fields and Risk of Childhood Leukemia
1From the Department of Preventive Medicine, University of Southern California School of Medicine Los Angeles, CA
2Department of Electrical Engineering, University Southern California School of Engineenng Los Angeles, CA
Reprint requests to Dr Stephanie London, University of Southern California Medical School PMB B306, 1420 San Pablo Street, Los Angeles CA 90033
The relation between exposure to electric and magnetic fields in the home, as assessed by measurements, wiring configuration, and self-reported appliance use, and risk of leukemia was investigated in a case-control study among children from birth to age 10 years in Los Angeles County, California. Cases were ascertained through a population-based tumor registry from 1980 to 1987. Controls were drawn from friends and by random digit dialing. Interviews were obtained from 232 cases and 232 controls. Available for analysis were measurements of the magnetic field in the child's bedroom over 24 hours or longer (164 cases and 144 controls), spot measurements of magnetic and electric fields (140 cases and 109 controls), and wiring configuration (219 cases and 207 controls). No clear associations between leukemia risk and measured magnetic or electric fields were seen. An association between the Denver Wertheimer-Leeper wiring configuration and childhood leukemia risk was observed (odds ratio for very high relative to very low current and underground configuration combined = 2.15, 95% confidence interval 1.08–4.28; p for trend = 0.008) and was not substantially altered by adjustment for potential confounding factors. Cases were more likely than controls to report use of several appliances that produce high electric and magnetic fields. Our results support an association between childhood leukemia risk and wiring configuration, but not direct measurements of electric and magnetic fields.Am J Epidemiol1991; 134:923–37.
electromagnetic radiation; environmental exposure; leukemia; occupational exposures
3Current address:National Institute of Occupational Safety and Health Cincinnati, OH
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