American Journal of Epidemiology Vol. 134, No. 2: 137-148
Copyright © 1991 by The Johns Hopkins University School of Hygiene and Public Health
other |
Factors Associated with High Density Lipoprotein Cholesterol in Japanese and American Telephone Executives
1 Department of Epidemiology, The Johns Hopkins University School of Hygiene and Public Health Baltimore, MD
2 Departments of Medicine, Epidemiology, and Health Policy and Management, The Johns Hopkins University School of Medicine and The Johns Hopkins University School of Hygiene and Public Health Baltimore, MD
3 Tokyo Central Health Administration Center, Nippon Telegraph and Telephone Public Corporation Tokyo, Japan
4 Departments of Epidemiology and Medicine, The Johns Hopkins University School of Hygiene and Public Health and The Johns Hopkins University School of Medicine Baltimore, MD
5 Department of Labor Medicine, Tokyo Central Health Administration Center, Nippon Telegraph and Telephone Public Corporation Tokyo, Japan
6 Department of Epidemiology, The Johns Hopkins University School of Hygiene and Public Health Baltimore, MD
Reprint requests to Dr. Michael J. Klag, The Welch Center for Prevention, Epidemiology, and Clinical Research, 600 N. Wolfe Street, Carnegie 291, Baltimore, MD 21205.
The association of plasma high density lipoprotein cholesterol (HDL cholesterol) with several factors was examined in a cross-sectional study of Japanese and American telephone executives. Mean HDL cholesterol levels were similar in both groups of men and were negatively associated with body mass index, smoking, and serum uric acid and positively associated with alcohol and exercise. These associations did not differ between the Japanese and the American men. The mean HDL cholesterol level was 4.2 mg/dl lower in the Japanese than in the American men after adjusting for age, body mass index, alcohol, smoking, exercise, and serum uric acid. The difference in HDL cholesterol between Japanese and American men in this study is inconsistent with the much lower coronary heart disease mortality in Japan and with previous comparison studies of these two populations. Most previous studies have not adjusted for important confounders, but the selective nature of our study groups may have also contributed to this inconsistency. These racial differences in HDL cholesterol may also be due to either genetic or unmeasured environmental and cultural differences. Given the similarity in HDL cholesterol levels between these two groups, our results suggest that HDL cholesterol does not play an important role in the lower coronary heart disease mortality in Japanese men. Am J Epidemiol 1991; 134: 137–48.
cardiovascular diseases; lipoproteins; HDL cholesterol; risk factors
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  Honors and Awards * Bibliography of Peer-Reviewed Journal Articles Am. J. Epidemiol., October 1, 2008; 168(7): 845 - 854. [Full Text] [PDF]
|
|
|
|
 |
|
 I. Saito, A. R Folsom, H. Aono, H. Ozawa, T. Ikebe, and T. Yamashita Comparison of fatal coronary heart disease occurrence based on population surveys in Japan and the USA Int. J. Epidemiol., October 1, 2000; 29(5): 837 - 844. [Abstract] [Full Text] [PDF]
|
|