American Journal of Epidemiology Vol. 132, No. 4: 717-722
Copyright © 1990 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
COFACTORS OF PROGRESSION TO ACQUIRED IMMUNODEFICIENCY SYNDROME IN A COHORT OF MALE SEXUAL CONTACTS OF MEN WITH HUMAN IMMUNODEFICIENCY VIRUS DISEASE
1Department of Preventive Medicine and Biostatistics, Faculty of Medicine, University of Toronto Toronto, Ontario, Canada
2Department of Medicine, Faculty of Medicine, University of Toronto Toronto, Ontario, Canada
3Departments of Statistics and Actuarial Science and Health Studies, University of Waterloo Waterloo, Ontario, Canada
4Department of Pediatrics, Faculty of Medicine, University of Toronto Toronto, Ontario, Canada
Reprint requests to Dr. Randall Coates, Department of Preventive Medicine and Biostatistics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada M5S 1A8
In a cohort of 249 male sexual contacts of men with acquired immunodeficiency syndrome (AIDS) or an AIDS-related condition in Toronto, Ontario, Canada, 143 cohort members were seropositive on enrollment and 16 seroconverted between initial recruitment in July 1984 to July 1985 and December 1988. Data on age, smoking and drinking status, recreational drug use, and history of sexually transmitted diseases and other diseases were obtained from interviews at induction and during follow-up on the cohort members every 3 months. Cox relative risk regression models, in which time was calculated from estimated date of human immunodeficiency virus (HIV) infection for seroprevalent cohort members and from 90 days prior to the first positive test for seroconverters, examined the potential effect of use of a variety of recreational drugs and the occurrence of selected infections on the risk of development of AIDS. Thirty-five cohort members developed AIDS while under study. No significant association with risk of progression to AIDS was noted for use of various recreational drugs (singly or in combination), history of specific infections, age at enrollment, or smoking and drinking status at enrollment. Only estimated duration of HIV infection appeared to be associated with increasing risk of development of AIDS.
acquired immunodeficiency syndrome; cohort studies; HIV
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  A S Furber, R Maheswaran, J N Newell, and C Carroll Is smoking tobacco an independent risk factor for HIV infection and progression to AIDS? A systemic review Sex Transm Inf, February 1, 2007; 83(1): 41 - 46. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. D. RILEY, R. E. CHAISSON, T. J. ROBNETT, J. VERTEFEUILLE, S. A. STRATHDEE, and D. VLAHOV Use of Audio Computer-assisted Self-Interviews to Assess Tuberculosis-related Risk Behaviors Am. J. Respir. Crit. Care Med., July 1, 2001; 164(1): 82 - 85. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Piette, T. J. Wachtel, V. Mor, and K. Mayer The Impact of Age on the Quality of Life in Persons with HIV Infection J Aging Health, May 1, 1995; 7(2): 163 - 178. [Abstract] [PDF]
|
|
|
|
 |
|
 A. J. Saah, D. R. Hoover, Y. Peng, J. P. Phair, B. Visscher, L. A. Kingsley, L. K. Schrager, the Multicenter AIDS Cohort Study, A. J. Saah, E. Taylor, et al. Predictors for Failure of Pneumocystis carinii Pneumonia Prophylaxis JAMA, April 19, 1995; 273(15): 1197 - 1202. [Abstract] [PDF]
|
|
|
|
 |
|
 A. Eskild and G. Petersen Cigarette Smoking and Drinking of Alcohol are not Associated with Rapid Progression to Acquired Immunodeficiency Syndrome among Homosexual Men in Norway Scand J Public Health, September 1, 1994; 22(3): 209 - 212. [Abstract] [PDF]
|
|