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American Journal of Epidemiology Vol. 132, No. 1: 77-82
Copyright © 1990 by The Johns Hopkins University School of Hygiene and Public Health


research-article

SERUM RETINOL AND AIRWAY OBSTRUCTION

ALFREDO MORABIA1, MARILYN J. S. MENKES1 *, GEORGE W. COMSTOCK1, and MELVYN S. TOCKMAN1,2

1Department of Epidemiology, Johns Hopkins University School of Hygiene and Public Health Baltimore, MD
2Department of Environmental Health Science, Johns Hopkins University School of Hygiene and Public Health Baltimore, MD

Reprint requests to Dr. George W. Comstock, Training Center for Public Health Research, Washington County Health Department, Box 2067, Hagerstown, MD 21742-2067

The relation of serum retinol and carotenoids to airway obstruction was investigated in a population-based study. Respiratory symptoms and the pulmonary function of 83 white males were assessed in 1979 5 years after their blood had been drawn. Airway obstruction in 1979, defined as a forced expiratory volume in 1 second which was equal to or less than 75% of the forced vital capacity, was associated with a decreased 1974 level of serum retinol.

carotene; forced expiratory flow rates; lung diseases, obstructive; vitamin A; vitamin E


Deceased.


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