American Journal of Epidemiology Vol. 132, No. 1: 33-40
Copyright © 1990 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
EFFECT OF DECAFFEINATED VERSUS REGULAR COFFEE ON SERUM LIPOPROTEINS
A 12-WEEK DOUBLE-BLIND TRIAL
1Human Nutrition Section, Department of Medicine, University of Nijmegen Nijmegen, The Netherlands
2Department of Human Nutrition, Agricultural University Wageningen, The Netherlands
3Division of General Internal Medicine, University of Nijmegen Nijmegen, The Netherlands
Reprint requests to Marijke van Dusseldorp, Human Nutrition Section, Department of Medicine, University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
Reports on the association between caffeine intake and serum cholesterol are inconsistent. In 1988, the authors examined the effect of decaffeinated versus regular coffee on serum lipids in 45 healthy volunteers from the general population living in or near Nijmegen, The Netherlands. Twenty-three women and 22 men aged 2545 years with a habitual intake of 46 cups of regular coffee per day participated in a randomized double-blind crossover trial. They received five cups of regular coffee each day for a period of 6 weeks and five cups of decaffeinated coffee for the next 6 weeks, or vice versa. The background diet was kept constant and was low in caffeine. Differences between the effects of decaffeinated and regular coffee on blood lipids were essentially zero; the effect on serum total cholesterol (±standard deviation) was 0.01 (±0.36) mmol/liter (0±14 mg/dl), that on high density lipoprotein cholesterol was 0.01 (±0.11) mmol/liter (0±4 mg/dl), and that on triglycerides was 0.03 (±0.29) mmol/liter (3±26 mg/dl). It was concluded that, in healthy adults, replacement of regular coffee by decaffeinated coffee has no effect on serum cholesterol and lipoproteins.
caffeine; cholesterol; clinical trials; coffee; lipoproteins; triglycerides
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
S. H. Jee, J. He, L. J. Appel, P. K. Whelton, I. Suh, and M. J. Klag Coffee Consumption and Serum Lipids: A Meta-Analysis of Randomized Controlled Clinical Trials Am. J. Epidemiol., February 15, 2001; 153(4): 353 - 362. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. M. Etherton and M. S. Kochar Coffee: Facts and Controversies Arch Fam Med, March 1, 1993; 2(3): 317 - 322. [Abstract] [PDF] |
||||
![]() |
G. R. Cooper, G. L. Myers, S. J. Smith, and R. C. Schlant Blood Lipid Measurements: Variations and Practical Utility JAMA, March 25, 1992; 267(12): 1652 - 1660. [Abstract] [PDF] |
||||
![]() |
R. E. Fried, D. M. Levine, P. O. Kwiterovich, E. L. Diamond, L. B. Wilder, T. F. Moy, and T. A. Pearson The Effect of Filtered-Coffee Consumption on Plasma Lipid Levels: Results of a Randomized Clinical Trial JAMA, February 12, 1992; 267(6): 811 - 815. [Abstract] [PDF] |
||||


