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American Journal of Epidemiology Vol. 130, No. 2: 404-409
Copyright © 1989 by The Johns Hopkins University School of Hygiene and Public Health

research-article

CONNECTIVE TISSUE DISEASE IN SOUTHEASTERN GEORGIA: A CASE-CONTROL STUDY OF ETIOLOGIC FACTORS

LAMBERTINA W. J. FRENI-TITULAER1,2, DELLE B. KELLEY1, ADAM G. GROW1, THOMAS W. McKINLEY3, FRANK C ARNETT4 and MARC C. HOCHBERG5

1Epidemiology and Surveillance Branch, Division of Chronic Disease Control, Center for Environmental Health and Injury Control, Centers for Disease Control Atlanta, GA.
2Current address. Epidemiology Program, Arkansas Department of Health Little Rock, AR
3Georgia Department of Human Resources Atlanta, GA.
4Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston Houston, TX
5Division of Molecular and Clinical Rheumatology, Department of Medicine, The Johns Hopkins University School of Medicine Baltimore, MD

Freni-Titulaer, L. W. J., D. B. Kelley (CDC, Adanta, GA 30333), A. G. Grow, T. W. Mckinley, F. C. Arnett, and M. C. Hochberg. Connective tissue disease in southeastern Georgia: a case-control study of etiologic factors.Am J Epidemiol 130;2:404-9

The authors conducted a population-based case-control study of connective tissue disease In a four-county area In southeastern Georgia. Interviews with 44 cases and 88 controls were conducted in September and October of 1988. The association with a family history of these disorders was reconfirmed, and a positive association with the use of hair dyes was found. A negative association was found with a family history of diabetes mellitus.

connective tissue diseases; lupus erythematosus; systemic; scieroderma; sys temic


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