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American Journal of Epidemiology Vol. 129, No. 4: 837-849
Copyright © 1989 by The Johns Hopkins University School of Hygiene and Public Health

research-article

USE OF MEDICAID DATA FOR PHARMACOEPIDEMIOLOGY

WAYNE A. RAY and MARIE R. GRIFFIN

1Department of Medicine and Department of Preventive Medicine and Clinical Epidemiology Chan ning Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
2Department of Medicine Roger Williams General Hospital, Brown Medical School, Providence, RI
3Department of Medicine Brockton-West Rox bury Veteran's Administration Medical Center, Har vard Medical School, Brockton, MA

Reprint requests to Dr. Wayne A. Ray

Because of the high prevalence of prescription drug use and the Incomplete understanding of drug effects at the time of Iicensing, ongoing epidemiologic monitoring is required to provide information for clinical and regulatory decisions. Data produced through the administration of Medicaid programs have been considered for this purpose because the computerized files include prescription and diagnostic information for large, defined populations. However, the limited amount of data available in the computerized files and the atypical demographic characteristics of Medicaid populations create formidable difficulties In the use of these data for pharmacoepldemiology. This paper reviews these methodolog ical problems and describes pragmatic solutions that have been developed through the ongoing use of these data bases for epidemiologic studies.

drug evaluation; epidemiologic methods; Medical Assistance; Title 19


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