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American Journal of Epidemiology Vol. 129, No. 4: 753-761
Copyright © 1989 by The Johns Hopkins University School of Hygiene and Public Health

research-article

EFFECT OF SCREENING AND TREATMENT ON IMPORTED INTESTINAL PARASITE INFECTIONS: RESULTS FROM A RANDOMIZED, CONTROLLED TRIAL

THERESA W. GYORKOS1,2,3,, LISE FRAPPIER-DAVIGNON2, J. DICK MAcLEAN3 and PIERRE VIENS4

1Department of Epidemiology and Biostatistics, McGill University Montréal, Québec, Canada H3A 1A2
2Department de 1Epidémiologie et de Médecine Preventive, Institut Armand-Frappier Laval-des Rapides, Québec, Canada
3McGill University Centre for Tropical Diseases Montreal General Hospital, Montréal, Québec, Canada
4Départment de Microbiologie et Immunologie, Faculté de Médecine, Université de Montréal Mon tréal, Québec, Canada

Reprint requests to Dr. Theresa W. Gyorkos at this address

A randomized, controlled trial was undertaken to evaluate the effects of a screening program for Intestinal parasite infection in newly arrived Southeast Asian refugees to Montral, Québec, Canada, during 1982–1983. Families as signed to the screened groups were examined, infected persons were treated and followed until they were infection-free, and all screened families were reexamined at six months. Families assigned to the control groups were examined at six months only. Statistically significant prevalence differences in unad justed and adjusted estimates over the six-month study period were found between screened persons and controls for each of three groups of refugees from Kampuchea, Laos, and Vietnam, respectively. in general, the greatest prevalence differences ascribed to the screening program were observed In hookworm and Ascarls lumbricoides infections. Continued high levels of Giardla lambila and Strongyloldes stercoralls infection were observed at six months; this raises concerns over the effective therapeutic management of infected persons, the risk of local transmission, and the relevance of screening for Intestinal parasites in new arrivals from endemic areas.

Ascarls; Entamoeba hlstolytlca; Glardla; hookworm infections; mass screening; parasites; refugees; Strongyloldes


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