American Journal of Epidemiology Vol. 128, No. 2: 381-388
Copyright © 1988 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
CONGENITAL HEART DISEASE: INCIDENCE IN THE FIRST YEAR OF LIFE
THE ALBERTA HERITAGE PEDIATRIC CARDIOLOGY PROGRAM
1Heritage Pediatric Cardiology Program, Division of Pediatric Cardiology, University of Alberta 2C3.00 Walter Mackenzie Centre, Edmonton, Alberta, Canada T6G 2R7
Reprint requests to Dr. Ruth L. Collins-Nakai
The Heritage Pediatric Cardiology Program is a regional study of patients with congenital heart disease in northern and central Alberta, Canada. Cases of congenital heart disease were confirmed by clinical examination by a pediatric cardiologist plus echocardiography (noninvasive criteria) with or without cardiac catheterization, cardiac surgery, or autopsy (invasive criteria). From 1981 to 1984 inclusive, 573 confirmed cases of congenital heart disease occurred in a population of 103,411 livebirths (5.54 and 3.36/1,000 livebirths using the noninvasive and the invasive criteria, respectively). This is significantly higher (p < 0.0001) than the rates found in the Baltimore-Washington Infant Study (3.69 and 2.38/1,000 livebirths for the noninvasive and invasive methods, respectively) or the New England Regional Infant Cardiac Program (2.20/1,000 livebirths using invasive methods). Although some lesions occur at rates similar to those found in these other registries, there are 4.4 times more double outlet right ventricles and 2.9 times more atrial septal defects in northern and central Alberta than were found in the New England Regional Infant Cardiac Program (p < 0.001). The overall congenital heart disease rate has increased 47% between 1981 and 1984, and the rate of ventricular septal defects has doubled during the same period in northern and central Alberta. No methodological bias was found to explain these higher and increasing rates.
abnormalities; infant
2 Present address: Department of Pediatric Cardiology, University of Aachen, Pauwelstr, 5100 Aachen, Federal Republic of Germany
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  M. Schwerzmann, O. Salehian, L. Harris, S. C. Siu, W. G. Williams, G. D. Webb, J. M. Colman, A. Redington, and C. K. Silversides Ventricular arrhythmias and sudden death in adults after a Mustard operation for transposition of the great arteries Eur. Heart J., August 1, 2009; 30(15): 1873 - 1879. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Y. Alton, C. M.T. Robertson, R. Sauve, A. Divekar, A. Nettel-Aguirre, S. Selzer, A. R. Joffe, I. M. Rebeyka, D. B. Ross, and Western Canadian Complex Pediatric Therapies Proje Early childhood health, growth, and neurodevelopmental outcomes after complete repair of total anomalous pulmonary venous connection at 6 weeks or younger J. Thorac. Cardiovasc. Surg., April 1, 2007; 133(4): 905 - 911. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z Kecskes and D W Cartwright Poor outcome of very low birthweight babies with serious congenital heart disease Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2002; 87(1): F31 - 33. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. I. E. Hoffman and S. Kaplan The incidence of congenital heart disease J. Am. Coll. Cardiol., June 19, 2002; 39(12): 1890 - 1900. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. D. Botto, A. Correa, and J. D. Erickson Racial and Temporal Variations in the Prevalence of Heart Defects Pediatrics, March 1, 2001; 107(3): 32e - 32. [Abstract] [Full Text]
|
|
|
|
 |
|
 V. Grech Patent Ductus Arteriosus in a Population-Based Study Asian Cardiovasc Thorac Ann, December 1, 1999; 7(4): 301 - 304. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. B Ainsworth, J. P Wyllie, and C. Wren Prevalence and clinical significance of cardiac murmurs in neonates Arch. Dis. Child. Fetal Neonatal Ed., January 1, 1999; 80(1): 43F - 45. [Abstract] [Full Text]
|
|
|
|
|
|
J. Gregory, A. Emslie, J. Wyllie, and C. Wren Examination for cardiac malformations at six weeks of age Arch. Dis. Child. Fetal Neonatal Ed., January 1, 1999; 80(1): 46F - 48. [Abstract] [Full Text]
|
|
|
|
|
|
C. Wren, S. Richmond, and L. Donaldson Presentation of congenital heart disease in infancy: implications for routine examination Arch. Dis. Child. Fetal Neonatal Ed., January 1, 1999; 80(1): 49F - 53. [Abstract] [Full Text]
|
|
|
|
 |
|
 C. J. Knott-Craig, R. C. Elkins, K. Ramakrishnan, D. A. Hartnett, M. M. Lane, E. D. Overholt, K. E. Ward, and J. R. Razook Associated Atrial Septal Defects Increase Perioperative Morbidity After Ventricular Septal Defect Repair in Infancy Ann. Thorac. Surg., March 1, 1995; 59(3): 573 - 578. [Abstract] [Full Text]
|
|