American Journal of Epidemiology Vol. 126, No. 6: 1093-1102
Copyright © 1987 by The Johns Hopkins University School of Hygiene and Public Health
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DIETARY FIBER AND REDUCED ISCREMIC HEART DISEASE MORTALITY RATES IT MEN AND WOMEN: A 12-YEAR PROSPECTIVE STUDY
1Department of Community and Family Medicine, School of Medicine, University of Cahfornia San Diego La Jolla, CA 92093
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The authors examined the relation between 24-hour dietary fiber Intake at baseline survey in 1972–1974 and subsequent 12-year ischemic heart disease mortality In a southern Californian population-based cohort of 859 men and women aged 50–79 years Relative risks of Ischemlc heart disease mortality in those with dietary fiber intake of 16 gm/24 hours or more compared with those with intake less than 16 gm/24 hours were 0.33 In men and 0.37 In women. A 6 gm increment in daily fiber intake was associated with a 25% reductIon in ischemlc heart disease mortality (p > 0.01). This effect was independent of other dietary variables, including calories, fat, cholesterol, protein, carbohydrate, alcohol, calcium, and potassium. Some, but not all, of this effect appears to be mediated through the known cardiovascular risk factors: after multivariafa adjustment for age, sex, blood pressure, plasma cholesterol, obesity, fasting plasma glucose, and cigarette smoking habit, the magnitude of the protective effect of fiber was reduced but still significant in both sexes combined. These findings support the hypothesis that high dietary fiber intake is protective for ischemlc heart disease mortality.
coronary disease; diet; dietary fiber; prospective studies; risk
2Current address: Department of Community Med icine, University of Cambridge School of Medicine, Addenbrookes Hospital, Cambridge, England
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