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American Journal of Epidemiology Vol. 126, No. 5: 803-812
Copyright © 1987 by The Johns Hopkins University School of Hygiene and Public Health


research-article

COFFEE CONSUMPTION AND MORTALITY IN THE CHICAGO WESTERN ELECTRIC COMPANY STUDY

DAN LEGRADY1, ALAN R. DYER2,, RICHARD B. SHEKELLE2, JEREMIAH STAMLER2, KIANG LIU2, OGLESBY PAUL4, MARK LEPPER5 and ANNE MACMILLAN SHRYOCK5

1Department of Pharmacy Practice, Creighton University School of Pharmacy and Allied Health Professions Omaha, NE.
2Department of Community Health and Preventive Medicine, Northwestern University Medical School Chicago, IL.
3School of Public Health, The University of Texas Health Science Center at Houston Houston, TX.
4Countway Library of Medicine, Harvard University Boston, MA.
5Rush-Presbyterian-St. Luke's Medical Center Chicago, IL.

Reprint requests to Dr. Alan R Dyer, Department of Community Health and Preventive Medicine, Northwestern University Medical School, 303 E. Chicago Avenue, Chicago, IL 60611

The relations between coffee consumption and 19-year mortality from all causes, coronary heart disease, and non-coronary causes were assessed in 1,910 white males aged 40–56 years in 1957–1958 from the Chicago Western Electric Company Study. Mortality rates, adjusted for age, serum cholesterol, diastolic blood pressure, and smoking status, were compared for those consum ing 0–1,2–3, 4–5, and 6+ cups of coffee per day; coffee intake, measured at the first anniversary examination, included both caffeinated and decaffeinated intake. Mortality from all causes was greatest in the highest and lowest intake groups. The Increased mortality in the 6+ cups per day group was due to coronary heart disease, while the increased mortality in the lowest intake group was due to noncoronary causes. The adjusted relative risk of coronary heart disease death for those drinking 6+ cups of coffee per day compared with those drinking less was 1.71 (95 per cent confidence limits 1.27, 2.30). This Increased risk of coronary heart disease death was present In both smokers and nonsmokers, with adjusted relative risks of 1.62 and 2.21, respectively (95 per cent confidence limits 1.17, 2.24 and 1.06, 4.62). The Increased mortality from non-coronary causes in the lowest intake group was due pnmarlly to increased mortality from cancer and cardiovascular diseases other than coronary heart disease. The results of this study support the hypothesis that those who drink 6+ cups of coffee per day may be at an increased risk of death from coronary heart disease.

coffee; coronary disease; mortality


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