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American Journal of Epidemiology Vol. 126, No. 3: 546-553
Copyright © 1987 by The Johns Hopkins University School of Hygiene and Public Health


research-article

CONFOUNDING CONFOUNDING1

D. A. GRAYSON

Grayson, D. A. (NH & MRC Social Psychiatry Research Unit, Australian National U., Canberra, ACT 2601, Australia). Confounding confounding. Am J Epidemiol 1987; 126:546–53.

Miettinen and Cook (Am J Epidemiol 1981;1 14:593–603) postulate that confounding is a result of exposure-strata dependence in the joint source population, irrespective of the effective parameter used. Boivin and Wacholder (Am J Epidemiol 1985;121:152–8) postulate that confounding is dependent on the additive structure of the crude effect parameter. Both of these conflicting principles are at variance with the familiar definition in terms of parameter bias. It is argued that the change-in-parameter definition is the only fundamental definition.

epidemiologic methods; statistics


1From the NH & MRC Social Psychiatry Research Unit, Australian National University, G.P.O. Box 4, Canberra, ACT 2601, Australia.


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