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American Journal of Epidemiology Vol. 125, No. 1: 140-149
Copyright © 1987 by The Johns Hopkins University School of Hygiene and Public Health


research-article

EPIDEMIOLOGY OF HEPATITIS B VIRUS INFECTION IN THE RURAL COMMUNITY OF TIP, SENEGAL

ELISABETH FERET1,2, BERNARD LAROUZE2, BIRON DIOP3, MOUSTAPHA SOW1, W. THOMAS LONDON1 and BARUCH S. BLUMBERG1

1Division of Clinical Research, Institute for Cancer Research, Fox Chase Cancer Center Philadelphia, PA 19111.
2Department d'Epidemiologie, Institut de Medecine et d'Epidemiologie Africaines, Hopital Claude Bernard Paris, France.
3Clinique Medicale de PHopital de Dantec, Faculte de Medecine et de Pharmacie de Dakar Dakar, Senegal

The distribution of responses to hepatitis B virus infection in the rural community of Tip, Senegal, has been determined. Children are rarely persistently infected before two years of age, at which time about 25% of the population are infected. Uninfected members continue to be at risk. Vaccination programs instituted at an early age could prevent infection in most of the population and considerably decrease the risk of chronic liver disease and primary cancer of the liver in adults.

hepatitis B virus; hepatoma; vaccination


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