American Journal of Epidemiology Vol. 125, No. 1: 101-109
Copyright © 1987 by The Johns Hopkins University School of Hygiene and Public Health
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DELAYED CHILDBEARING: NO EVIDENCE FOR INCREASED RISK OF LOW BIRTH WEIGHT AND PRETERM DELIVERY1
*Reprint requests to Dr. Michael B. Bracken, Department of Epidemiology and Public Health, Yale University School of Medicine, 60 College Street, New Haven CT 06510
Prior studies of the effect of increased maternal age on reproductive outcomes in primiparous women have often ignored the possible Influence on this relation of more frequent histories of spontaneous abortion and infertility in older women. When these histories are taken into account, the present study of 1,382 white primiparous women who had live singleton deliveries at Yale-New Haven Hospital finds no evidence for an increased risk of low birth weight (relative risk (RR) = 1.06, 95% confidence interval (CI) = 0.38–2.94) or preterm delivery (RR = 1.07, 95% CI = 0.50–2.24) in women delivering at age 30 years or more compared with younger women. Mean birth weight (0 = -19 g, p = 0.57) and gestational age (/? = -0.16 weeks, p = 0.34) were also not significantly affected by older maternal primipartty. Women aged 35 years or more had twice the rate of preterm births compared with women under age 30, although this result was not statistically significant in this data set (RR = 2.07, 95% CI = 0.67–6.35). Other confounding variables were taken into account
infant; low birth weight; infant; premature; maternal age
1From the Perinatal Epidemiology Unit of the Departments of Epidemiology and Public Health, and Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT.
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