American Journal of Epidemiology Vol. 124, No. 6: 977-985
Copyright © 1986 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
RISK FACTORS FOR NOSOCOMIAL URINARY TRACT INFECTION
1Channing Laboratory, Hospital Epidemiology Units and Departments of Medicine, Brigharn and Women's Hospital and New England Deaconess Hospital Boston. MA.
2Departments of Medicine, Preventive Medicine and Clinical Epidemiology, Harvard Medical School Boston. MA.
3Present address: Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health Baltimore. MD.
In a prospective study carried out in June 1979-April 1981, 134 of 1,458 adult inpatients at New England Deaconess Hospital, Boston, Massachusetts, acquired 136 urinary tract infections during 1,474 indwelling bladder catheterizations. Multiple logistic regression analysis identified nine factors that were signficantly associated with acquisition of infection: duration of catheterization, lack of systemic antibiotic during short catheter courses, lack of urinemeter drainage, female sex, diabetes mellitus, microbial colonization of the drainage bag, serum creatinine>2 mg/dl at the time of catheterization, the reason for catheterization, and the use of catheters with sealed collection junctions when no antibiotic was administered. When potential risk factors were considered individually, without adjusting for the influence of other factors, infection was also signficantly assodated with 11 other factors, including several that have been previously reported as risk factors for catheter-associated urinary tract infections; however, these associations were no longer significant atter adjustment for one or more of the nine factors noted above. These findings suggest approaches to surveillance, prevention, and research activities. They also strongly support the widely held but poorly documented belief that persons with diabetes are more susceptible to urinary tract infection than are persons without diabetes.
catheters; indwelling; cross infection; urinary tract infections; morbidity
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  E. M. Kojic and R. O. Darouiche Candida Infections of Medical Devices Clin. Microbiol. Rev., April 1, 2004; 17(2): 255 - 267. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. Gerberding Hospital-Onset Infections: A Patient Safety Issue Ann Intern Med, October 15, 2002; 137(8): 665 - 670. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. J. Boyko, S. D. Fihn, D. Scholes, C.-L. Chen, E. H. Normand, and P. Yarbro Diabetes and the Risk of Acute Urinary Tract Infection Among Postmenopausal Women Diabetes Care, October 1, 2002; 25(10): 1778 - 1783. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Safdar and D. G. Maki The Commonality of Risk Factors for Nosocomial Colonization and Infection with Antimicrobial-Resistant Staphylococcus aureus, Enterococcus, Gram-Negative Bacilli, Clostridium difficile, and Candida Ann Intern Med, June 4, 2002; 136(11): 834 - 844. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Eggimann and D. Pittet Infection Control in the ICU Chest, December 1, 2001; 120(6): 2059 - 2093. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Saint, D. L. Veenstra, S. D. Sullivan, C. Chenoweth, and A. M. Fendrick The Potential Clinical and Economic Benefits of Silver Alloy Urinary Catheters in Preventing Urinary Tract Infection Arch Intern Med, September 25, 2000; 160(17): 2670 - 2675. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. A. Tambyah and D. G. Maki The Relationship Between Pyuria and Infection in Patients With Indwelling Urinary Catheters: A Prospective Study of 761 Patients Arch Intern Med, March 13, 2000; 160(5): 673 - 677. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. A. Tambyah and D. G. Maki Catheter-Associated Urinary Tract Infection Is Rarely Symptomatic: A Prospective Study of 1497 Catheterized Patients Arch Intern Med, March 13, 2000; 160(5): 678 - 682. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. R. Johnson, P. Delavari, and M. Azar Activities of a Nitrofurazone-Containing Urinary Catheter and a Silver Hydrogel Catheter against Multidrug-Resistant Bacteria Characteristic of Catheter-Associated Urinary Tract Infection Antimicrob. Agents Chemother., December 1, 1999; 43(12): 2990 - 2995. [Abstract] [Full Text]
|
|
|
|
|
|
S. Saint and B. A. Lipsky Preventing Catheter-Related Bacteriuria: Should We? Can We? How? Arch Intern Med, April 26, 1999; 159(8): 800 - 808. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Joshi and D. Milfred The Use and Misuse of New Antibiotics: A Perspective Arch Intern Med, March 27, 1995; 155(6): 569 - 577. [Abstract] [PDF]
|
|
|
|
 |
|
 W. E. Stamm and T. M. Hooton Management of Urinary Tract Infections in Adults N. Engl. J. Med., October 28, 1993; 329(18): 1328 - 1334. [Full Text]
|
|
|
|
|
|
T. S. Huth, J. P. Burke, R. A. Larsen, D. C. Classen, and L. E. Stevens Clinical Trial of Junction Seals for the Prevention of Urinary Cather--Associated Bacteriuria Arch Intern Med, April 1, 1992; 152(4): 807 - 812. [Abstract] [PDF]
|
|