American Journal of Epidemiology Vol. 124, No. 6: 916-925
Copyright © 1986 by The Johns Hopkins University School of Hygiene and Public Health
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EPIDEMIOLOGIC ASSOCIATIONS WITH NUCLEAR, CORTICAL, AND POSTERIOR SUBCAPSULAR CATARACTS
1Biometry and Epidemiology Program, National Eye Institute, National Institutes of Health Bethesda MD.
2Current address: Department of Ophthalmology, Georgetown University Washington, DC.
1Send reprint requests to Ms. Rita Hiller, Biom-etry and Epidemiology Program, National Eye Insti-tute, Bldg. 31, Rm. 6A16, Bethesda, MD 20892.
Hiller, R. (National Eye Institute, Bethesda, MD 20892), H. D. Sperduto, and F. Ederer. Epidemiologic associations with nuclear, cortical, and posterior subcap sular cataracts. Am J EpkJemlol 1986;124:916–25.
Data from the 1971–1972 National Health and Nutrition Examination Survey were used to examine the associations between specific cataract types and age, race, sex, number of years spent in school, diabetes, systolic blood pressure, urban versus rural residence, and average daily ultraviolet spectrum B (UV-B) radiation counts at the site of examination. Separate comparisons were made of persons with no lens changes (n = 1,299) and persons with cortical (n = 55), nuclear (n = 104), and posterior subcapsular cataracts (n = 18). Persons with more than one type of cataract were excluded from the analysis. Cortical cata racts were associated with age (relative risk (RR) = 11.4 for age 70 years vs. age 50 years), race (RR = 3.5 for blacks vs. whites), sex (RR = 3.0 for women vs. men), educational achlevement(RR = 1.8 for less than nIne years of schooling vs. college), and UV-B count (RR = 3.6 for 6.0 × 1O3 counts vs. 2.6 X 1O10 counts). Nuclear cataracts were associated with age (RR = 38.6 for age 70 years vs. age 50 years), race (RR = 1.8 for black vs. white), and residence (RR = 1.6 for rural vs. urban). Posterior subcapsular cataracts were associated with diabetes (RR = 6.6 for diabetes present vs. diabetes absent) and systolic blood pressure (RR =2.2 for 160 mmHg vs. 120 mmHg). Cortical cataracts were more common In women and more often found in locations with Increased UV-B radiation counts than either nuclear or posterior subcapsular cataracts. In diabetics, the risk of posterior subcapsular cataracts was greater than the risk of nuclear cataracts (p <0.05) and also appeared to be greater than the risk of cortical cataracts (p =0.06).
aged; blacks; blood pressure; blacks; diabetes mellitus; education; sex; ultraviolet rays
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