American Journal of Epidemiology Vol. 124, No. 4: 633-642
Copyright © 1986 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
ASSOCIATION OF LOW BIRTH WEIGHT WITH PASSIVE SMOKE EXPOSURE IN PREGNANCY1
2Reprint requests to Terry R. Martin at present address: Massachusetts Department of Public Health, Division of Health Statistics and Research, 150 Tremont Street, Boston, MA 02111
In a prospective study of 3,891 antenatal patients at Yale-New Haven Hospital between 1980 and 1982, one fourth (23.6%) had not smoked cigarettes during pregnancy but had been exposed to sidestream smoke for at least two hours per day. Among the nonsmokers, passive smoke exposure was significantly related to delivering a low birth weight (<2,500 g) newborn. This relation only occurred in term (
37 weeks) deliveries. Compared with unexposed women, the relative risk of low birth weight after adjustment for confounding factors was 2.17 (95% confidence interval (Cl) = 1.05–4.50). Those exposed to passive smoke delivered infants 24 g lighter on average. There was no additive effect of passive smoking on smokers themselves. Repeating the analysis on all women with term deliveries, therefore, resulted in a slightly diminished risk of low birth weight due to passive smoking of 1.52 (95% Cl = 0.90–2.56). The risk of low birth weight at term due to direct cigarette smoking was 3.54 (95% Cl = 1.62–7.71). Gestational age was unrelated to passive smoking, which appears to exert its effect primarily through growth retardation in term newborns.
infant; low birth weight; infant; premature; smoking; passive
1 From the Perinatal Epidemiology Unit of the Departments of Epidemiology and Public Health, and Obstetrics and Gynecology, Yale University Medical School, New Haven, CT.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  D. Best, Committee on Environmental Health, Committee on Native American Child Health, and Committee on Adolescence Secondhand and Prenatal Tobacco Smoke Exposure Pediatrics, November 1, 2009; 124(5): e1017 - e1044. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J Leonardi-Bee, A Smyth, J Britton, and T Coleman Environmental tobacco smoke and fetal health: systematic review and meta-analysis Arch. Dis. Child. Fetal Neonatal Ed., September 1, 2008; 93(5): F351 - F361. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Melkonian, H. Eckelhoefer, M. Wu, Y. Wang, C. Tong, K. Riveles, and P. Talbot Growth and Angiogenesis Are Inhibited in Vivo in Developing Tissues by Pyrazine and Its Derivatives Toxicol. Sci., October 1, 2003; 75(2): 393 - 401. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Rogers and B. D. Abbott Screening for Developmental Toxicity of Tobacco Smoke Constituents Toxicol. Sci., October 1, 2003; 75(2): 227 - 228. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. B. Bracken, K. Belanger, W. O. Cookson, E. Triche, D. C. Christiani, and B. P. Leaderer Genetic and Perinatal Risk Factors for Asthma Onset and Severity: A Review and Theoretical Analysis Epidemiol. Rev., December 1, 2002; 24(2): 176 - 189. [Full Text] [PDF]
|
|
|
|
|
|
L. Ji, G. Melkonian, K. Riveles, and P. Talbot Identification of Pyridine Compounds in Cigarette Smoke Solution That Inhibit Growth of the Chick Chorioallantoic Membrane Toxicol. Sci., September 1, 2002; 69(1): 217 - 225. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H Wennborg, L Bodin, H Vainio, and G Axelsson Solvent use and time to pregnancy among female personnel in biomedical laboratories in Sweden Occup. Environ. Med., April 1, 2001; 58(4): 225 - 231. [Abstract] [Full Text]
|
|
|
|
 |
|
 E. Nelson, K. Jodscheit, and Y. Guo Maternal passive smoking during pregnancy and fetal developmental toxicity. Part 1: gross morphological effects Human and Experimental Toxicology, April 1, 1999; 18(4): 252 - 256. [Abstract] [PDF]
|
|
|
|
|
|
W Hanke, J Kalinka, E Florek, and W Sobala Passive smoking and pregnancy outcome in central Poland Human and Experimental Toxicology, April 1, 1999; 18(4): 265 - 271. [Abstract] [PDF]
|
|
|
|
|
|
J Klein and G Koren Hair analysis-a biological marker for passive smoking in pregnancy and childhood Human and Experimental Toxicology, April 1, 1999; 18(4): 279 - 282. [Abstract] [PDF]
|
|
|
|
 |
|
 L. M Davies Publicans and passive smoking: a survey of publicans' views on tobacco smoke in their workplaces Health Education Journal, January 1, 1999; 58(3): 271 - 279. [Abstract] [PDF]
|
|
|
|
 |
|
 R. J. Witorsch and P. Witorsch Environmental Tobacco Smoke and Birthweight of Offspring: A Critical Review and Analysis of the Epidemiological Literature Indoor and Built Environment, July 1, 1996; 5(4): 219 - 231. [Abstract] [PDF]
|
|
|
|
 |
|
 A. G. Mainous III and W. J. Hueston Passive Smoke and Low Birth Weight: Evidence of a Threshold Effect Arch Fam Med, October 1, 1994; 3(10): 875 - 878. [Abstract] [PDF]
|
|
|
|
 |
|
 C. Eliopoulos, J. Klein, M. K. Phan, B. Knie, M. Greenwald, D. Chitayat, and G. Koren Hair Concentrations of Nicotine and Cotinine in Women and Their Newborn Infants JAMA, February 23, 1994; 271(8): 621 - 623. [Abstract] [PDF]
|
|
|
|
 |
|
 R. B. Hakim and J. M. Tielsch Maternal Cigarette Smoking During Pregnancy: A Risk Factor for Childhood Strabismus Arch Ophthalmol, October 1, 1992; 110(10): 1459 - 1462. [Abstract] [PDF]
|
|