American Journal of Epidemiology Vol. 124, No. 2: 254-261
Copyright © 1986 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
OSTEOPOROSIS AND THE RISK OF HIP FRACTURE
1 Department of Medical Statistics and Epidemiology, Mayo Clinic and Mayo Foundation Rochester, MN
2 Department of Laboratory Medicine, Mayo Clinic and Mayo Foundation Rochester, MN
3 Division of Endocrinology, Department of Internal Medicine, Mayo Clinic and Mayo Foundation Rochester, MN
Reprint requests to Dr. L. Joseph Melton, Department of Medical Statistics and Mayo Clinic, 200 First Street SW, Rochester, MN 55905
The incidence of cervical and intertrochanteilc proximal femur fractures at various levels of cervical and intertrochanteric bone mineral density, respectively, was estimated by using population-based data from ongoing studies of osteoporosis and fractures among women residing in Rochester, Minnesota. Hip fractures were uncommon among women with femoral bone density 
1.O g/cm2 but their frequency increased as bone density declined below that point at both ternoral sites. The incidence of cervical femur fractures was estimated at 8.3 per 1,000 person-years among women with cervical bone density <0.6 g/cm2 while the estimated incidence of intertrochanterlc femur fractures reached 16.6 per 1,000 person-years among those with intertrochanteric bone density <0.6 g/cm2 This new approach to the assessment of fracture risk from bone mineral density measurements indicates that osteoporosis is an important underlying cause of hip fractures.
hip fractures; osteoporosis
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