American Journal of Epidemiology Vol. 122, No. 5: 750-761
Copyright © 1985 by The Johns Hopkins University School of Hygiene and Public Health
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CHOLESTEROL, HIGH DENSITY LIPOPROTEIN CHOLESTEROL AND TRIGLYCERIDES DURING PUBERTY: THE OSLO YOUTH STUDY
1Division of Epidemiology, University of Minnesota Stadium Gate 27,611 Beacon Street, S.E., Minneapolia, MN 55455
2Institute of Preventive Medicine, University of Oslo Oslo, Norway
Reprint requests to Dr. Grethe S.Tell
The relationships of serum total cholesterol, high density lipoprotein (HDL) cholesterol and fasting triglycerides (adjusted for body mass index, wt/ht2) with stages of pubertal development were examined in a Norwegian population of 920 adolescents, aged 10 to 16 years. For 13-and 14-year-olds, all five stages of Tanner's maturity index were represented. For the whole population, total serum cholesterol showed a larger decrease when related to sexual maturity stage than to chronologic age. For females, HDL cholesterol and triglycerides increased significantly when related to age in years; this was not found when related to the maturity index. Triglycerides showed a larger increase when related to chronologic age in males as compared with sexual maturity stage. Both among 13-and 14-year-old males, the most mature had significantly lower values for total cholesterol than the least mature. For 12-year-old males, HDL cholesterol decreased significantly with increasing sexual maturation. Among females, the more mature 12-year-olds had significantly lower values for total cholesterol compared with the less mature. Early maturing 13-, 14- and 15-16-year-olds had lower levels of HDL cholesterol compared with late maturers. These findings suggest that age in years may be a poor index of development in adolescents and that a measure of physiologic developmental age should be included in epidemiologic studies of serum lipids among adolescents.
cholesterol; lipoproteins; HDL; pyberty; triglycerides
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